The likelihood of being helped or harmed as a patient-centred tool to assess cyclin dependent kinase 4/6 inhibitors clinical impact and safety in metastatic breast cancer: a systematic review and sensitivity-analysisResearch in context

The likelihood of being helped or harmed as a patient-centred tool to assess cyclin dependent kinase 4/6 inhibitors clinical impact and safety in metastatic breast cancer: a systematic review and sensitivity-analysisResearch in context

Summary: Background: In hormone-receptor positive/HER2-negative metastatic breast cancer (mBC) no randomized comparisons are available between CDK4/6 inhibitors. We undertook this systematic review and meta-analysis to assess the reliability of the likelihood of being helped or harmed (LHH). Method...

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Bibliographic Details
Main Authors: Luca Mastrantoni, Armando Orlandi, Antonella Palazzo, Giovanna Garufi, Alessandra Fabi, Gennaro Daniele, Diana Giannarelli, Giampaolo Tortora, Emilio Bria
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:EClinicalMedicine
Subjects:
Metastatic breast cancer
CDK4/6 inhibitors
LHH
NNT
NNH
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023000019

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