A Small Molecule Promoting Neural Differentiation Suppresses Cancer Stem Cells in Colorectal Cancer

A Small Molecule Promoting Neural Differentiation Suppresses Cancer Stem Cells in Colorectal Cancer

Cancer stem cells (CSCs) are a tumor cell subpopulation that drives tumor progression and metastasis, leading to a poor overall survival of patients. In colorectal cancer (CRC), the hyper-activation of Wnt/β-catenin signaling by a mutation of both adenomatous polyposis coli (APC) and <i>K-Ras&...

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Bibliographic Details
Main Authors:	Jung Kyu Choi, Ihn-Sil Kwak, Sae-Bom Yoon, Heeyeong Cho, Byoung-San Moon
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	Biomedicines
Subjects:	colorectal cancer cancer stem cell neural progenitor cell Wnt/β-catenin <i>K-Ras</i>
Online Access:	https://www.mdpi.com/2227-9059/10/4/859

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