Cocrystals of Isoniazid with Polyphenols: Mechanochemical Synthesis and Molecular Structure

Cocrystals of Isoniazid with Polyphenols: Mechanochemical Synthesis and Molecular Structure

Isoniazid is used as anti-tuberculosis drug which possesses functional groups capable of forming hydrogen bonds. A series of cocrystals of isoniazid (INH) with polyphenolic coformers such as catechol (CAT), orcinol (ORC), 2-methylresorcinol (MER), pyrogallol (PYR), and phloroglucinol (PLG) were prep...

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Bibliographic Details
Main Authors: Juan Saulo González-González, Ana María Monserrat Martínez-Santiago, Francisco Javier Martínez-Martínez, María José Emparán-Legaspi, Armando Pineda-Contreras, Marcos Flores-Alamo, Héctor García-Ortega
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Crystals
Subjects:
isoniazid
cocrystal
polyphenols
hydrogen bond
mechanochemistry
Online Access:https://www.mdpi.com/2073-4352/10/7/569

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