Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics
Local anesthetics are frequently used by dentists to relieve localized discomfort of the patient and improve treatment conditions. The risk of paresthesia after local anesthesia is frequently encountered in dental clinics. The neurotoxicity of local anesthetics is a disregarded factor in paresthesia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023052398 |
| _version_ | 1827892248749015040 |
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| author | Yong-zhen Tan Rong-jia Shi Bo-wen Ke Ya-ling Tang Xin-hua Liang |
| author_facet | Yong-zhen Tan Rong-jia Shi Bo-wen Ke Ya-ling Tang Xin-hua Liang |
| author_sort | Yong-zhen Tan |
| collection | DOAJ |
| description | Local anesthetics are frequently used by dentists to relieve localized discomfort of the patient and improve treatment conditions. The risk of paresthesia after local anesthesia is frequently encountered in dental clinics. The neurotoxicity of local anesthetics is a disregarded factor in paresthesia. The review summarizes the types of common local anesthetics, incidence and influencing factors of paresthesia after local anesthesia, and systematically describes the neurotoxicity mechanisms of dental local anesthetic. Innovative strategies may be developed to lessen the neurotoxicity and prevent paresthesia following local anesthesia with the support of a substantial understanding of paresthesia and neurotoxicity. |
| first_indexed | 2024-03-12T21:37:08Z |
| format | Article |
| id | doaj.art-0d3bafe530714a5d91eb64b3cbd87966 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-12T21:37:08Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-0d3bafe530714a5d91eb64b3cbd879662023-07-27T05:58:18ZengElsevierHeliyon2405-84402023-07-0197e18031Paresthesia in dentistry: The ignored neurotoxicity of local anestheticsYong-zhen Tan0Rong-jia Shi1Bo-wen Ke2Ya-ling Tang3Xin-hua Liang4State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaLaboratory of Anesthesiology & Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, ChinaState Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, Department of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Corresponding author.State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, China; Corresponding author.Local anesthetics are frequently used by dentists to relieve localized discomfort of the patient and improve treatment conditions. The risk of paresthesia after local anesthesia is frequently encountered in dental clinics. The neurotoxicity of local anesthetics is a disregarded factor in paresthesia. The review summarizes the types of common local anesthetics, incidence and influencing factors of paresthesia after local anesthesia, and systematically describes the neurotoxicity mechanisms of dental local anesthetic. Innovative strategies may be developed to lessen the neurotoxicity and prevent paresthesia following local anesthesia with the support of a substantial understanding of paresthesia and neurotoxicity.http://www.sciencedirect.com/science/article/pii/S2405844023052398ParesthesiaNeurotoxicityLocal anestheticsDentistry |
| spellingShingle | Yong-zhen Tan Rong-jia Shi Bo-wen Ke Ya-ling Tang Xin-hua Liang Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics Heliyon Paresthesia Neurotoxicity Local anesthetics Dentistry |
| title | Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics |
| title_full | Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics |
| title_fullStr | Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics |
| title_full_unstemmed | Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics |
| title_short | Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics |
| title_sort | paresthesia in dentistry the ignored neurotoxicity of local anesthetics |
| topic | Paresthesia Neurotoxicity Local anesthetics Dentistry |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023052398 |
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