The cGAS-STING pathway-dependent sensing of mitochondrial DNA mediates ocular surface inflammation
Abstract The innate immune response is the main pathophysiological process of ocular surface diseases exposed to multiple environmental stresses. The epithelium is central to the innate immune response, but whether and how innate immunity is initiated by ocular epithelial cells in response to variou...
Main Authors: | Weijie Ouyang, Shoubi Wang, Dan Yan, Jieli Wu, Yunuo Zhang, Wei Li, Jiaoyue Hu, Zuguo Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-09-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-023-01624-z |
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