Early deviant behaviour as a dimension trait and endophenotype in schizophrenia
Background: In psychiatry, there is still a lack of objective biological diagnostic measurements. It is important to investigate measurements or symptom dimensions that can inform diagnostic assessments and allow for a more personalised approach to patients. Aim: To discuss how early deviant behavi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
AOSIS
2022-04-01
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| Series: | South African Journal of Psychiatry |
| Subjects: | |
| Online Access: | https://sajp.org.za/index.php/sajp/article/view/1747 |
| _version_ | 1818200628120256512 |
|---|---|
| author | Johannes L. Roos Carla Kotzé |
| author_facet | Johannes L. Roos Carla Kotzé |
| author_sort | Johannes L. Roos |
| collection | DOAJ |
| description | Background: In psychiatry, there is still a lack of objective biological diagnostic measurements. It is important to investigate measurements or symptom dimensions that can inform diagnostic assessments and allow for a more personalised approach to patients.
Aim: To discuss how early deviant behaviour (EDB) may be seen as a possible continuous symptom dimension trait and endophenotype in schizophrenia.
Methods: Conducting a commentary review by highlighting some important findings from available literature.
Results: Findings regarding EDB in schizophrenia in a South African genetic sample point towards EDB as a progressive subtype of schizophrenia, with very early onset of illness (even prior to the psychotic symptomatology) and a genetic form of illness.
Conclusion: Valuable information can be gained by enquiring into EDB and viewing it as a continuous symptom dimension trait and endophenotype during the psychiatric diagnostic interview. |
| first_indexed | 2024-12-12T02:40:41Z |
| format | Article |
| id | doaj.art-0d3d6285003044ef83f4992b6939f897 |
| institution | Directory Open Access Journal |
| issn | 1608-9685 2078-6786 |
| language | English |
| last_indexed | 2024-12-12T02:40:41Z |
| publishDate | 2022-04-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Journal of Psychiatry |
| spelling | doaj.art-0d3d6285003044ef83f4992b6939f8972022-12-22T00:41:11ZengAOSISSouth African Journal of Psychiatry1608-96852078-67862022-04-01280e1e610.4102/sajpsychiatry.v28i0.1747605Early deviant behaviour as a dimension trait and endophenotype in schizophreniaJohannes L. Roos0Carla Kotzé1Department of Psychiatry, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; and, Weskoppies Psychiatric Hospital, PretoriaDepartment of Psychiatry, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; and, Weskoppies Psychiatric Hospital, PretoriaBackground: In psychiatry, there is still a lack of objective biological diagnostic measurements. It is important to investigate measurements or symptom dimensions that can inform diagnostic assessments and allow for a more personalised approach to patients. Aim: To discuss how early deviant behaviour (EDB) may be seen as a possible continuous symptom dimension trait and endophenotype in schizophrenia. Methods: Conducting a commentary review by highlighting some important findings from available literature. Results: Findings regarding EDB in schizophrenia in a South African genetic sample point towards EDB as a progressive subtype of schizophrenia, with very early onset of illness (even prior to the psychotic symptomatology) and a genetic form of illness. Conclusion: Valuable information can be gained by enquiring into EDB and viewing it as a continuous symptom dimension trait and endophenotype during the psychiatric diagnostic interview.https://sajp.org.za/index.php/sajp/article/view/1747early onsetdeviant behaviourschizophreniaendophenotypecontinuous symptom dimension |
| spellingShingle | Johannes L. Roos Carla Kotzé Early deviant behaviour as a dimension trait and endophenotype in schizophrenia South African Journal of Psychiatry early onset deviant behaviour schizophrenia endophenotype continuous symptom dimension |
| title | Early deviant behaviour as a dimension trait and endophenotype in schizophrenia |
| title_full | Early deviant behaviour as a dimension trait and endophenotype in schizophrenia |
| title_fullStr | Early deviant behaviour as a dimension trait and endophenotype in schizophrenia |
| title_full_unstemmed | Early deviant behaviour as a dimension trait and endophenotype in schizophrenia |
| title_short | Early deviant behaviour as a dimension trait and endophenotype in schizophrenia |
| title_sort | early deviant behaviour as a dimension trait and endophenotype in schizophrenia |
| topic | early onset deviant behaviour schizophrenia endophenotype continuous symptom dimension |
| url | https://sajp.org.za/index.php/sajp/article/view/1747 |
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