MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.

In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly affect the life cycles of viruses bearing sequence complementary targets, a finding recently exploited to ameliorate toxicities of vaccines and oncolytic viruses. To elucidate the mechanisms underlying m...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Elizabeth J Kelly, Elizabeth M Hadac, Bryan R Cullen, Stephen J Russell
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2010-03-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC2841627?pdf=render