MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.

In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly affect the life cycles of viruses bearing sequence complementary targets, a finding recently exploited to ameliorate toxicities of vaccines and oncolytic viruses. To elucidate the mechanisms underlying m...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Elizabeth J Kelly, Elizabeth M Hadac, Bryan R Cullen, Stephen J Russell
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Public Library of Science (PLoS) 2010-03-01
Σειρά:PLoS Pathogens
Διαθέσιμο Online:http://europepmc.org/articles/PMC2841627?pdf=render