MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.

In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly affect the life cycles of viruses bearing sequence complementary targets, a finding recently exploited to ameliorate toxicities of vaccines and oncolytic viruses. To elucidate the mechanisms underlying m...

Description complète

Détails bibliographiques
Auteurs principaux: Elizabeth J Kelly, Elizabeth M Hadac, Bryan R Cullen, Stephen J Russell
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2010-03-01
Collection:PLoS Pathogens
Accès en ligne:http://europepmc.org/articles/PMC2841627?pdf=render