MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.

In addition to modulating the function and stability of cellular mRNAs, microRNAs can profoundly affect the life cycles of viruses bearing sequence complementary targets, a finding recently exploited to ameliorate toxicities of vaccines and oncolytic viruses. To elucidate the mechanisms underlying m...

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Dettagli Bibliografici
Autori principali: Elizabeth J Kelly, Elizabeth M Hadac, Bryan R Cullen, Stephen J Russell
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2010-03-01
Serie:PLoS Pathogens
Accesso online:http://europepmc.org/articles/PMC2841627?pdf=render