The Effect of Phytoestrogens on Menopause Symptoms: A Systematic Review
Background: Menopause is a major concern in women’s productivity. Low estrogen in this period brings about many complications. Besides hot flashes, which are the most common menopausal symptom, women might experience vaginal dryness, sleeping disorders, depression, low bone density, as well as cardi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Isfahan University of Medical Sciences
2018-06-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/9503 |
| Summary: | Background: Menopause is a major concern in women’s productivity. Low estrogen in this period brings about many complications. Besides hot flashes, which are the most common menopausal symptom, women might experience vaginal dryness, sleeping disorders, depression, low bone density, as well as cardiovascular diseases. To decrease these life-threatening complications, postmenopausal women receive varying treatments including hormone replacement therapy (HRT). Among the replacement therapies, phytoestrogens are special. The present study was conducted to investigate the effect of phytoestrogens on menopause symptoms.
Methods: This was a systematic review of the previous studies. The search was conducted through Science Direct, Scopus, PubMed, EMBASE, Google Scholar, Scientific Information Database (SID) and IranMedex databases during 2013-2017, using the keywords menopause, climacteric, phytoestrogens, isoflavones, non-steroidal estrogen, and menopausal symptoms.
Findings: Ultimately, 25 articles, including 7 meta-analyses, 14 clinical trials, 2 cohort studies, and 2 cross-sectional ones were found focusing on the effect of phytoestrogens on menopause symptoms. These studies measured the effect of phytoestrogens on depression, vaginite atrofica, hot flashes, cardiovascular diseases indices and blood pressure, bone status, and the risk of cancer in women.
Conclusion: The results revealed that having estrogenic effects, the phytoestrogens could be considered as a proposed treatment to relieve menopause symptoms in the hope of improving women’s quality of life during this time span. |
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| ISSN: | 1027-7595 1735-854X |