Genetic dissection of the RNA polymerase II transcription cycle

Genetic dissection of the RNA polymerase II transcription cycle

How DNA sequence affects the dynamics and position of RNA Polymerase II (Pol II) during transcription remains poorly understood. Here, we used naturally occurring genetic variation in F1 hybrid mice to explore how DNA sequence differences affect the genome-wide distribution of Pol II. We measured th...

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Bibliographic Details
Main Authors: Shao-Pei Chou, Adriana K Alexander, Edward J Rice, Lauren A Choate, Charles G Danko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
RNA polymerase II
transcription
gene expression
Online Access:https://elifesciences.org/articles/78458

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