Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila
For many applications knowledge of context-specific gene regulatory networks (GRNs) is desirable, but their inference remains a challenge. Here, the authors introduce a method for construction of context-specific GRNs, and apply it to construct sex-specific Drosophila GRNs.
Main Authors: | Yijie Wang, Dong-Yeon Cho, Hangnoh Lee, Justin Fear, Brian Oliver, Teresa M. Przytycka |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-06382-z |
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