Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and Asymmetry

Abstract Circulating tumor cell clusters (CTC clusters) are potent initiators of metastasis and potentially useful clinical markers for patients with cancer. Although there are numerous devices developed to isolate individual circulating tumor cells from blood, these devices are ineffective at captu...

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Bibliographic Details
Main Authors: Sam H. Au, Jon Edd, Amy E. Stoddard, Keith H. K. Wong, Fabio Fachin, Shyamala Maheswaran, Daniel A. Haber, Shannon L. Stott, Ravi Kapur, Mehmet Toner
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01150-3