Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies

Objectives: To describe blood lead levels (BLLs) and their distribution among children in Broken Hill, New South Wales (NSW), at each of the scheduled testing points aligned with childhood immunisation and to determine how BLLs change over time for individual children. These data can inform action t...

Full description

Bibliographic Details
Main Authors: David M Lyle, Frances T Boreland, Stephen J Quartermain
Format: Article
Language:English
Published: Sax Institute 2022-03-01
Series:Public Health Research & Practice
Subjects:
Online Access:https://doi.org/10.17061/phrp31122107
_version_ 1818157839640690688
author David M Lyle
Frances T Boreland
Stephen J Quartermain
author_facet David M Lyle
Frances T Boreland
Stephen J Quartermain
author_sort David M Lyle
collection DOAJ
description Objectives: To describe blood lead levels (BLLs) and their distribution among children in Broken Hill, New South Wales (NSW), at each of the scheduled testing points aligned with childhood immunisation and to determine how BLLs change over time for individual children. These data can inform action to prevent future lead exposure in Broken Hill children. Study type: Retrospective longitudinal study. Methods: Data were extracted from the Lead Management Program ACCESS database on children born between 2009 and 2015 and living in Broken Hill. BLLs were calculated using capillary blood collected via finger prick, classified according to specific blood lead thresholds and grouped according to the testing schedule. A subset of children tested at each of the first three annual testing points provided data to determine the blood lead trajectories for individual Broken Hill children. Data were analysed using SPSS and ArcGIS. Results: At the first test at 12 months, around half the children recorded a BLL of <5 µg/dL, one in three had a BLL of 5–9 µg/dL and one in five had a BLL of ≥10 µg/dL. A similar pattern was observed for subsequent test points at 18 months, 2 years, 3 years and 4 years. Of the 336 children who had results recorded at each of the 12-month, 2-year and 3-year test points, BLLs in around one-third remained below the recommended threshold of 5 µg/dL. Another one-third of these children had at least one test result ≥10 µg/dL, and the BLL in the remainder did not exceed 5–9 µg/dL at any of the test points. The geospatial distribution of children with very high BLLs shows clustering of these children in some localities, as well as their widespread distribution throughout Broken Hill. Conclusions: It should be possible to keep BLLs below 5 µg/dL for the majority of young children in Broken Hill throughout their preschool years. This could be achieved by an integrated prevention strategy that includes population-level interventions such as targeted zonal remediation for high-risk areas and early intervention for individuals during the first 12 months and beyond, particularly for those who may not benefit directly from targeted zonal remediation. Routinely collected data could be used to guide the development, and monitor the effectiveness, of these interventions.
first_indexed 2024-12-11T15:20:34Z
format Article
id doaj.art-0d499ae534024187a9227be2657b5877
institution Directory Open Access Journal
issn 2204-2091
language English
last_indexed 2024-12-11T15:20:34Z
publishDate 2022-03-01
publisher Sax Institute
record_format Article
series Public Health Research & Practice
spelling doaj.art-0d499ae534024187a9227be2657b58772022-12-22T01:00:23ZengSax InstitutePublic Health Research & Practice2204-20912022-03-0132110.17061/phrp31122107Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategiesDavid M Lyle 0Frances T Boreland1Stephen J Quartermain 2 Broken Hill University Department of Rural Health, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Broken Hill, NSW, AustraliaBroken Hill Environmental Lead Program, NSW Environment Protection Authority, AustraliaBroken Hill University Department of Rural Health, Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Broken Hill, NSW, AustraliaObjectives: To describe blood lead levels (BLLs) and their distribution among children in Broken Hill, New South Wales (NSW), at each of the scheduled testing points aligned with childhood immunisation and to determine how BLLs change over time for individual children. These data can inform action to prevent future lead exposure in Broken Hill children. Study type: Retrospective longitudinal study. Methods: Data were extracted from the Lead Management Program ACCESS database on children born between 2009 and 2015 and living in Broken Hill. BLLs were calculated using capillary blood collected via finger prick, classified according to specific blood lead thresholds and grouped according to the testing schedule. A subset of children tested at each of the first three annual testing points provided data to determine the blood lead trajectories for individual Broken Hill children. Data were analysed using SPSS and ArcGIS. Results: At the first test at 12 months, around half the children recorded a BLL of <5 µg/dL, one in three had a BLL of 5–9 µg/dL and one in five had a BLL of ≥10 µg/dL. A similar pattern was observed for subsequent test points at 18 months, 2 years, 3 years and 4 years. Of the 336 children who had results recorded at each of the 12-month, 2-year and 3-year test points, BLLs in around one-third remained below the recommended threshold of 5 µg/dL. Another one-third of these children had at least one test result ≥10 µg/dL, and the BLL in the remainder did not exceed 5–9 µg/dL at any of the test points. The geospatial distribution of children with very high BLLs shows clustering of these children in some localities, as well as their widespread distribution throughout Broken Hill. Conclusions: It should be possible to keep BLLs below 5 µg/dL for the majority of young children in Broken Hill throughout their preschool years. This could be achieved by an integrated prevention strategy that includes population-level interventions such as targeted zonal remediation for high-risk areas and early intervention for individuals during the first 12 months and beyond, particularly for those who may not benefit directly from targeted zonal remediation. Routinely collected data could be used to guide the development, and monitor the effectiveness, of these interventions.https://doi.org/10.17061/phrp31122107blood leadbroken hill
spellingShingle David M Lyle
Frances T Boreland
Stephen J Quartermain
Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies
Public Health Research & Practice
blood lead
broken hill
title Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies
title_full Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies
title_fullStr Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies
title_full_unstemmed Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies
title_short Blood lead levels among Broken Hill children born 2009–2015: a longitudinal study to inform prevention strategies
title_sort blood lead levels among broken hill children born 2009 2015 a longitudinal study to inform prevention strategies
topic blood lead
broken hill
url https://doi.org/10.17061/phrp31122107
work_keys_str_mv AT davidmlyle bloodleadlevelsamongbrokenhillchildrenborn20092015alongitudinalstudytoinformpreventionstrategies
AT francestboreland bloodleadlevelsamongbrokenhillchildrenborn20092015alongitudinalstudytoinformpreventionstrategies
AT stephenjquartermain bloodleadlevelsamongbrokenhillchildrenborn20092015alongitudinalstudytoinformpreventionstrategies