Ribociclib for the treatment of hormone-positive HER2-negative breast cancer

Breast cancer steadily holds leading market positions in the malignancy morbidity and mortality pattern. The treatment of metastatic breast cancer remains an extremely topical issue, when its aim is not only to prolong the patient’s life, but also to preserve its quality. Due to advances in molecula...

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Bibliographic Details
Main Authors: I. P. Ganshina, D. A. Filonenko, O. O. Gordeeva, E. V. Lubennikova, I. V. Kolyadina, A. A. Mescheryakov
Format: Article
Language:Russian
Published: Remedium Group LLC 2019-06-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/3055
Description
Summary:Breast cancer steadily holds leading market positions in the malignancy morbidity and mortality pattern. The treatment of metastatic breast cancer remains an extremely topical issue, when its aim is not only to prolong the patient’s life, but also to preserve its quality. Due to advances in molecular diagnostics, it has become possible to use several new classes of drugs in recent times. CDK4/6 inhibitors that demonstrate high efficacy in the first-line therapy for luminal metastatic breast cancer is one of these groups. This review presents data from recent registration studies and a description of observations from our own clinical experience.
ISSN:2079-701X
2658-5790