New approaches for diagnosis of dry eye disease

We reviewed the literature for different diagnostic approaches for dry eye disease (DED) including the most recent advances, contradictions and promising diagnostic tools and technique. We performed a broad literature search for articles discussing different methods for diagnosis of DED including as...

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Main Authors: Abdelrahman M. Elhusseiny, Ali A. Khalil, Reem H. El Sheikh, Mohammad A. Bakr, Mohamed Gaber Eissa, Yasmine M. El Sayed
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2019-10-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2019/10/20191015.pdf
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author Abdelrahman M. Elhusseiny
Ali A. Khalil
Reem H. El Sheikh
Mohammad A. Bakr
Mohamed Gaber Eissa
Yasmine M. El Sayed
author_facet Abdelrahman M. Elhusseiny
Ali A. Khalil
Reem H. El Sheikh
Mohammad A. Bakr
Mohamed Gaber Eissa
Yasmine M. El Sayed
author_sort Abdelrahman M. Elhusseiny
collection DOAJ
description We reviewed the literature for different diagnostic approaches for dry eye disease (DED) including the most recent advances, contradictions and promising diagnostic tools and technique. We performed a broad literature search for articles discussing different methods for diagnosis of DED including assessment of tear osmolarity, tear film stability, ocular biomarkers and others. Articles indexed in PubMed and google scholar were included. With the growing cosmetic industry, environmental pollution, and booming of digital screens, DED is becoming more prevalent. Its multifactorial etiology renders the diagnosis challenging and invites the emergence of new diagnostic tools and tests. Diagnostic tools can be classified, based on the parameter they measure, into tear film osmolarity, functional visual acuity, tear volume, tear turnover, tear film stability, tear film composition, ocular biomarkers and others. Although numerous methods exist, the most accurate diagnosis can be reached through combining the results of more than one test. Many reported tests have shown potential as diagnostic/screening tools, however, require more research to prove their diagnostic power, alone or in combination. Future research should focus on identifying and measuring parameters that are the most specific to DED diagnosis.
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spelling doaj.art-0d4d1c1ff5ca43b3a0d3299bb3fcc1c32022-12-22T01:12:17ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982019-10-0112101618162810.18240/ijo.2019.10.15New approaches for diagnosis of dry eye diseaseAbdelrahman M. Elhusseiny0Ali A. Khalil1Reem H. El Sheikh2Mohammad A. Bakr3Mohamed Gaber Eissa4Yasmine M. El Sayed5Department of Ophthalmology, Kasr Al Ainy School of medicine, Cairo University, Dokki 12611, Egypt; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17 Street, Miami, FL 33136, USAFaculty of Medicine, American University of Beirut, Beirut 2341, LebanonDepartment of Ophthalmology, Kasr Al Ainy School of medicine, Cairo University, Dokki 12611, EgyptDepartment of Ophthalmology, Kasr Al Ainy School of medicine, Cairo University, Dokki 12611, EgyptDepartment of Ophthalmology, Kasr Al Ainy School of medicine, Cairo University, Dokki 12611, EgyptDepartment of Ophthalmology, Kasr Al Ainy School of medicine, Cairo University, Dokki 12611, EgyptWe reviewed the literature for different diagnostic approaches for dry eye disease (DED) including the most recent advances, contradictions and promising diagnostic tools and technique. We performed a broad literature search for articles discussing different methods for diagnosis of DED including assessment of tear osmolarity, tear film stability, ocular biomarkers and others. Articles indexed in PubMed and google scholar were included. With the growing cosmetic industry, environmental pollution, and booming of digital screens, DED is becoming more prevalent. Its multifactorial etiology renders the diagnosis challenging and invites the emergence of new diagnostic tools and tests. Diagnostic tools can be classified, based on the parameter they measure, into tear film osmolarity, functional visual acuity, tear volume, tear turnover, tear film stability, tear film composition, ocular biomarkers and others. Although numerous methods exist, the most accurate diagnosis can be reached through combining the results of more than one test. Many reported tests have shown potential as diagnostic/screening tools, however, require more research to prove their diagnostic power, alone or in combination. Future research should focus on identifying and measuring parameters that are the most specific to DED diagnosis.http://www.ijo.cn/en_publish/2019/10/20191015.pdfdry eye diseasetear film stabilitytear osmolarityocular biomarkers
spellingShingle Abdelrahman M. Elhusseiny
Ali A. Khalil
Reem H. El Sheikh
Mohammad A. Bakr
Mohamed Gaber Eissa
Yasmine M. El Sayed
New approaches for diagnosis of dry eye disease
International Journal of Ophthalmology
dry eye disease
tear film stability
tear osmolarity
ocular biomarkers
title New approaches for diagnosis of dry eye disease
title_full New approaches for diagnosis of dry eye disease
title_fullStr New approaches for diagnosis of dry eye disease
title_full_unstemmed New approaches for diagnosis of dry eye disease
title_short New approaches for diagnosis of dry eye disease
title_sort new approaches for diagnosis of dry eye disease
topic dry eye disease
tear film stability
tear osmolarity
ocular biomarkers
url http://www.ijo.cn/en_publish/2019/10/20191015.pdf
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