Identification of phenolic constituents and antioxidant activity of Aloe barbadensis flower extracts

Aloe vera (Aloe barbadensis Miller) has been used as topical and oral therapeutic. This research highlights the phenolic constituents’ profile and antioxidant activity of 70% ethanol extracts of Aloe vera flower for the first time. The ethanol-based extracts showed the inhibition for linoleic acid o...

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Bibliographic Details
Main Authors: Trishna Debnath, Mithun Ghosh, Young Min Lee, Narayan Chandra Deb Nath, Kwang-Geun Lee, Beong Ou Lim
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Food and Agricultural Immunology
Subjects:
Online Access:http://dx.doi.org/10.1080/09540105.2017.1358254
Description
Summary:Aloe vera (Aloe barbadensis Miller) has been used as topical and oral therapeutic. This research highlights the phenolic constituents’ profile and antioxidant activity of 70% ethanol extracts of Aloe vera flower for the first time. The ethanol-based extracts showed the inhibition for linoleic acid oxidation and free radical-induced DNA damage. Among about 11 phenolic constituents of the extract, identified by using high performance liquid chromatography (HPLC), the content of vanillic acid was highest, corresponding to strong antioxidant activities of the extract. The extracts elevated superoxide dismutase, catalase, and glutathione peroxidase enzymes activities in the liver tissue of hydrogen peroxide-treated BALB/c mice. The radical-scavenging activities of the extracts were well-correlated to the total phenolic content. Therefore, Aloe bardadensis flower might be an effective source of natural antioxidant.
ISSN:0954-0105
1465-3443