Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation

Prolonged activation of S6K1 does not suppress IRS or PI-3 kinase signaling during muscle cell differentiation

<p>Abstract</p> <p>Background</p> <p>Myogenesis in C2C12 cells requires the activation of the PI3K/mTOR signaling pathways. Since mTOR signaling can feedback through S6K1 to inhibit the activation of PI3K, the aim of this work was to assess whether feedback from S6K1 pl...

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Bibliographic Details
Main Authors:	MacKenzie Matthew G, Philp Andrew, Hamilton D Lee, Baar Keith
Format:	Article
Language:	English
Published:	BMC 2010-05-01
Series:	BMC Cell Biology
Online Access:	http://www.biomedcentral.com/1471-2121/11/37

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