Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial

Abstract Background High-flow nasal oxygenation and the oxygen reserve index (ORI), which is a non-invasive and innovative modality that reflects the arterial oxygen content, are used in general anaesthesia. This study compares the preoxygenation efficiency (measured by the ORI) of high-flow nasal o...

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Main Authors: Sujung Park, So Yeon Kim, Min-Soo Kim, Wyun Kon Park, Hyo-Jin Byon, Hyun Joo Kim
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-023-02126-9
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author Sujung Park
So Yeon Kim
Min-Soo Kim
Wyun Kon Park
Hyo-Jin Byon
Hyun Joo Kim
author_facet Sujung Park
So Yeon Kim
Min-Soo Kim
Wyun Kon Park
Hyo-Jin Byon
Hyun Joo Kim
author_sort Sujung Park
collection DOAJ
description Abstract Background High-flow nasal oxygenation and the oxygen reserve index (ORI), which is a non-invasive and innovative modality that reflects the arterial oxygen content, are used in general anaesthesia. This study compares the preoxygenation efficiency (measured by the ORI) of high-flow nasal oxygenation and facemask ventilation during the induction process. Methods This single-centre, two-group, randomised controlled trial included 197 patients aged ≥ 20 years who underwent orotracheal intubation for general anaesthesia for elective surgery. The patients were randomly allocated to receive preoxygenation via facemask ventilation or high-flow nasal oxygenation. The ORI was measured and compared between both groups. Results The ORI increased during preoxygenation in all patients. At 1 min of preoxygenation, the ORI was significantly higher in the high-flow nasal oxygenation group (0.34 ± 0.33) than in the facemask ventilation group (0.21 ± 0.28; P = 0.003). The highest ORI was not significantly different between the two groups (0.68 ± 0.25 in the high-flow nasal oxygenation group vs. 0.70 ± 0.28 in the facemask ventilation group; P = 0.505). Conclusions High-flow nasal oxygenation results in an oxygenation status similar to that provided by facemask ventilation during the induction process of general anaesthesia; therefore, high-flow nasal oxygenation is a feasible preoxygenation method. Trial Registration Clinicaltrials.gov (NCT04291339).
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spelling doaj.art-0d54b99480d74b438fc81308c3849c372023-05-14T11:25:40ZengBMCBMC Anesthesiology1471-22532023-05-012311910.1186/s12871-023-02126-9Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trialSujung Park0So Yeon Kim1Min-Soo Kim2Wyun Kon Park3Hyo-Jin Byon4Hyun Joo Kim5Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of MedicineDepartment of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of MedicineDepartment of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of MedicineDepartment of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of MedicineDepartment of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of MedicineDepartment of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of MedicineAbstract Background High-flow nasal oxygenation and the oxygen reserve index (ORI), which is a non-invasive and innovative modality that reflects the arterial oxygen content, are used in general anaesthesia. This study compares the preoxygenation efficiency (measured by the ORI) of high-flow nasal oxygenation and facemask ventilation during the induction process. Methods This single-centre, two-group, randomised controlled trial included 197 patients aged ≥ 20 years who underwent orotracheal intubation for general anaesthesia for elective surgery. The patients were randomly allocated to receive preoxygenation via facemask ventilation or high-flow nasal oxygenation. The ORI was measured and compared between both groups. Results The ORI increased during preoxygenation in all patients. At 1 min of preoxygenation, the ORI was significantly higher in the high-flow nasal oxygenation group (0.34 ± 0.33) than in the facemask ventilation group (0.21 ± 0.28; P = 0.003). The highest ORI was not significantly different between the two groups (0.68 ± 0.25 in the high-flow nasal oxygenation group vs. 0.70 ± 0.28 in the facemask ventilation group; P = 0.505). Conclusions High-flow nasal oxygenation results in an oxygenation status similar to that provided by facemask ventilation during the induction process of general anaesthesia; therefore, high-flow nasal oxygenation is a feasible preoxygenation method. Trial Registration Clinicaltrials.gov (NCT04291339).https://doi.org/10.1186/s12871-023-02126-9Anesthetic inductionApneic oxygenationFacemask ventilationHigh-flow nasal cannulaHigh-flow nasal oxygenationOxygen reserve index
spellingShingle Sujung Park
So Yeon Kim
Min-Soo Kim
Wyun Kon Park
Hyo-Jin Byon
Hyun Joo Kim
Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial
BMC Anesthesiology
Anesthetic induction
Apneic oxygenation
Facemask ventilation
High-flow nasal cannula
High-flow nasal oxygenation
Oxygen reserve index
title Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial
title_full Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial
title_fullStr Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial
title_full_unstemmed Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial
title_short Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial
title_sort comparison of preoxygenation efficiency measured by the oxygen reserve index between high flow nasal oxygenation and facemask ventilation a randomised controlled trial
topic Anesthetic induction
Apneic oxygenation
Facemask ventilation
High-flow nasal cannula
High-flow nasal oxygenation
Oxygen reserve index
url https://doi.org/10.1186/s12871-023-02126-9
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