The Impact of the Microbiome on Resistance to Cancer Treatment with Chemotherapeutic Agents and Immunotherapy

The Impact of the Microbiome on Resistance to Cancer Treatment with Chemotherapeutic Agents and Immunotherapy

Understanding the mechanisms of resistance to therapy in human cancer cells has become a multifaceted limiting factor to achieving optimal cures in cancer patients. Besides genetic and epigenetic alterations, enhanced DNA damage repair activity, deregulation of cell death, overexpression of transmem...

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Bibliographic Details
Main Authors: Aneta Sevcikova, Nikola Izoldova, Viola Stevurkova, Barbora Kasperova, Michal Chovanec, Sona Ciernikova, Michal Mego
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
microbiome
chemotherapy
immunotherapy
treatment resistance
microbiota modulations
probiotics
Online Access:https://www.mdpi.com/1422-0067/23/1/488

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