Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients

Relevance. There is a limited number of publications reporting outcomes of primary large joint arthroplasty in patients with human immunodeficiency virus (HIV). The authors were unable to find papers on revision arthroplasty in patients with periprosthetic infection. Purpose of the study — to evalua...

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Main Authors: A. S. Tryapichnikov, A. M. Ermakov, N. M. Klyushin, Yu. V. Ababkov, A. B. Stepanayn, A. N. Koyushkov
Format: Article
Language:Russian
Published: Vreden Russian Research Institute of Traumatology and Orthopedics 2019-12-01
Series:Travmatologiâ i Ortopediâ Rossii
Subjects:
Online Access:https://journal.rniito.org/jour/article/view/1321
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author A. S. Tryapichnikov
A. M. Ermakov
N. M. Klyushin
Yu. V. Ababkov
A. B. Stepanayn
A. N. Koyushkov
author_facet A. S. Tryapichnikov
A. M. Ermakov
N. M. Klyushin
Yu. V. Ababkov
A. B. Stepanayn
A. N. Koyushkov
author_sort A. S. Tryapichnikov
collection DOAJ
description Relevance. There is a limited number of publications reporting outcomes of primary large joint arthroplasty in patients with human immunodeficiency virus (HIV). The authors were unable to find papers on revision arthroplasty in patients with periprosthetic infection. Purpose of the study — to evaluate short term outcomes after revision arthroplasty in HIV-positive patients with periprosthetic infection of the hip and knee joint. Materials and methods. 13 HIV-positive patients with periprosthetic infection of the hip (10 cases) and knee (3 cases) joint underwent treatment in the period from 2015 to 2019. Patients were examined by clinical, laboratory and roentgenological methods. Harris Hip Score and Knee Society Score were used for evaluation prior to and after the surgery. Results. Mean follow up period was 21,4±2,6 months. Successful two-stage treatment was performed in two (15,4%) out of 13 patients with periprosthetic infection. In 5 cases (38,5%) control over infection was achieved by resection arthroplasty, and in one case (7,7%) – by arthrodesis. Five patients (38,5%) refused from interchange of spacer to prosthesis. Mean Harris Hip score demonstrated insignificant increase postoperatively — from 45,3±2,2 to 52,2±4,15 (р = 0,2). Conclusion. Despite following the international protocols for treatment of implant-associated infection the infection recurrence rate in HIV-positive patients in the asymptomatic phase remains very high. Efficiency of twostage treatment using antibacterial spacers in the present group of patients amounted only to 15,4%.
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spelling doaj.art-0d57ff42df664314840e2e7b99bb35bb2022-12-21T22:13:48ZrusVreden Russian Research Institute of Traumatology and OrthopedicsTravmatologiâ i Ortopediâ Rossii2311-29052542-09332019-12-0125411712510.21823/2311-2905-2019-25-4-117-125830Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive PatientsA. S. Tryapichnikov0A. M. Ermakov1N. M. Klyushin2Yu. V. Ababkov3A. B. Stepanayn4A. N. Koyushkov5Ilizarov Russian Scientific Center “Restorative Traumatology and Orthopedics”Ilizarov Russian Scientific Center “Restorative Traumatology and Orthopedics”Ilizarov Russian Scientific Center “Restorative Traumatology and Orthopedics”, Tyumen State Medical UniversityIlizarov Russian Scientific Center “Restorative Traumatology and Orthopedics”Ilizarov Russian Scientific Center “Restorative Traumatology and Orthopedics”Ilizarov Russian Scientific Center “Restorative Traumatology and Orthopedics”Relevance. There is a limited number of publications reporting outcomes of primary large joint arthroplasty in patients with human immunodeficiency virus (HIV). The authors were unable to find papers on revision arthroplasty in patients with periprosthetic infection. Purpose of the study — to evaluate short term outcomes after revision arthroplasty in HIV-positive patients with periprosthetic infection of the hip and knee joint. Materials and methods. 13 HIV-positive patients with periprosthetic infection of the hip (10 cases) and knee (3 cases) joint underwent treatment in the period from 2015 to 2019. Patients were examined by clinical, laboratory and roentgenological methods. Harris Hip Score and Knee Society Score were used for evaluation prior to and after the surgery. Results. Mean follow up period was 21,4±2,6 months. Successful two-stage treatment was performed in two (15,4%) out of 13 patients with periprosthetic infection. In 5 cases (38,5%) control over infection was achieved by resection arthroplasty, and in one case (7,7%) – by arthrodesis. Five patients (38,5%) refused from interchange of spacer to prosthesis. Mean Harris Hip score demonstrated insignificant increase postoperatively — from 45,3±2,2 to 52,2±4,15 (р = 0,2). Conclusion. Despite following the international protocols for treatment of implant-associated infection the infection recurrence rate in HIV-positive patients in the asymptomatic phase remains very high. Efficiency of twostage treatment using antibacterial spacers in the present group of patients amounted only to 15,4%.https://journal.rniito.org/jour/article/view/1321periprosthetic infectionrevision arthroplastyhiv-infection
spellingShingle A. S. Tryapichnikov
A. M. Ermakov
N. M. Klyushin
Yu. V. Ababkov
A. B. Stepanayn
A. N. Koyushkov
Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients
Travmatologiâ i Ortopediâ Rossii
periprosthetic infection
revision arthroplasty
hiv-infection
title Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients
title_full Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients
title_fullStr Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients
title_full_unstemmed Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients
title_short Treatment Outcomes of Periprosthetic Joint Infection in HIV-positive Patients
title_sort treatment outcomes of periprosthetic joint infection in hiv positive patients
topic periprosthetic infection
revision arthroplasty
hiv-infection
url https://journal.rniito.org/jour/article/view/1321
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AT yuvababkov treatmentoutcomesofperiprostheticjointinfectioninhivpositivepatients
AT abstepanayn treatmentoutcomesofperiprostheticjointinfectioninhivpositivepatients
AT ankoyushkov treatmentoutcomesofperiprostheticjointinfectioninhivpositivepatients