Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study
Introduction: Post infectious glomerulonephritis remains the most common cause leading to the majority of hospital admissions in children of developing countries like ours. The aim of our study was to find the prevalence of post infectious glomerulonephritis, study the clinical profile, biochemical...
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Nepal Medical Association
2024-03-01
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| Series: | Journal of Nepal Medical Association |
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| Online Access: | https://www.jnma.com.np/jnma/index.php/jnma/article/view/8554 |
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| author | Mandira Shrestha Romila Chimoriya Amrit Dhungel Sujit Koirala Rohit Bhatta Bijay Basnet |
| author_facet | Mandira Shrestha Romila Chimoriya Amrit Dhungel Sujit Koirala Rohit Bhatta Bijay Basnet |
| author_sort | Mandira Shrestha |
| collection | DOAJ |
| description |
Introduction: Post infectious glomerulonephritis remains the most common cause leading to the majority of hospital admissions in children of developing countries like ours. The aim of our
study was to find the prevalence of post infectious glomerulonephritis, study the clinical profile, biochemical changes and its complication in children admitted in a tertiary care hospital of Nepal.
Methods: This descriptive cross-sectional study of children admitted at a tertiary care hospital was done from May 2020 till May 2023. A census sampling method was used and sample of 1554 children was taken. Detailed socio demographic data, clinical findings and laboratory investigations were done. Data analysis was done using SPSS software and the results obtained are shown in the form of frequencies along with percentages.
Results: Among 1554 patients, the prevalence of acute post-infectious glomerulonephritis was found to be 63 (4.05%) (3.07-5.03 at 95% Confidence Interval). The mean age of the patients was 9.06±3.48 years. Antistreptolysin O titer was raised in 34 (54%) patients, while low serum C3 was observed in 39 (61.90%) patients with acute post-infectious glomerulonephritis.
Conclusions: Acute post-infectious glomerulonephritis (APIGN) remains a notable health concern in children, particularly in developing countries like Nepal. This highlights the need for ongoing surveillance, prevention strategies, and effective management protocols to address this burden effectively.
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| institution | Directory Open Access Journal |
| issn | 0028-2715 1815-672X |
| language | English |
| last_indexed | 2025-03-20T10:14:47Z |
| publishDate | 2024-03-01 |
| publisher | Nepal Medical Association |
| record_format | Article |
| series | Journal of Nepal Medical Association |
| spelling | doaj.art-0d58350aec5d477b9f16c869fe19bae32024-09-23T18:38:50ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2024-03-016227210.31729/jnma.8554Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional StudyMandira Shrestha0Romila Chimoriya1Amrit Dhungel2Sujit Koirala3Rohit Bhatta4Bijay Basnet5Nepal Medical college and teaching hospital, Jorpati, Kathmandu, NepalNepal Medical college and teaching hospital, Jorpati, Kathmandu, NepalNepal Medical college and teaching hospital, Jorpati, Kathmandu, NepalNepal Medical college and teaching hospital, Jorpati, Kathmandu, NepalNepal Medical college and teaching hospital, Jorpati, Kathmandu, NepalNepal Medical college and teaching hospital, Jorpati, Kathmandu, Nepal Introduction: Post infectious glomerulonephritis remains the most common cause leading to the majority of hospital admissions in children of developing countries like ours. The aim of our study was to find the prevalence of post infectious glomerulonephritis, study the clinical profile, biochemical changes and its complication in children admitted in a tertiary care hospital of Nepal. Methods: This descriptive cross-sectional study of children admitted at a tertiary care hospital was done from May 2020 till May 2023. A census sampling method was used and sample of 1554 children was taken. Detailed socio demographic data, clinical findings and laboratory investigations were done. Data analysis was done using SPSS software and the results obtained are shown in the form of frequencies along with percentages. Results: Among 1554 patients, the prevalence of acute post-infectious glomerulonephritis was found to be 63 (4.05%) (3.07-5.03 at 95% Confidence Interval). The mean age of the patients was 9.06±3.48 years. Antistreptolysin O titer was raised in 34 (54%) patients, while low serum C3 was observed in 39 (61.90%) patients with acute post-infectious glomerulonephritis. Conclusions: Acute post-infectious glomerulonephritis (APIGN) remains a notable health concern in children, particularly in developing countries like Nepal. This highlights the need for ongoing surveillance, prevention strategies, and effective management protocols to address this burden effectively. https://www.jnma.com.np/jnma/index.php/jnma/article/view/8554children; edema; hypertension; Poststreptococcus glomerulonephritis, Post infectious glomerulonephritis |
| spellingShingle | Mandira Shrestha Romila Chimoriya Amrit Dhungel Sujit Koirala Rohit Bhatta Bijay Basnet Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study Journal of Nepal Medical Association children; edema; hypertension; Poststreptococcus glomerulonephritis, Post infectious glomerulonephritis |
| title | Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study |
| title_full | Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study |
| title_fullStr | Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study |
| title_full_unstemmed | Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study |
| title_short | Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study |
| title_sort | acute post infectious glomerulonephritis in children admitted to a tertiary care hospital a descriptive cross sectional study |
| topic | children; edema; hypertension; Poststreptococcus glomerulonephritis, Post infectious glomerulonephritis |
| url | https://www.jnma.com.np/jnma/index.php/jnma/article/view/8554 |
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