Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations
Restless legs syndrome (RLS) is a neurological disorder that responds to dopaminergic drugs, indicating a common pathophysiology with Parkinson's disease (PD). The prevalence of RLS was estimated in a group of PD patients and its clinical and biochemical characteristics were analysed. Forty-eig...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2010-12-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600007&lng=en&tlng=en |
| _version_ | 1817977697572225024 |
|---|---|
| author | Tiago Machado Guerreiro Danilo Ryuko Cândido Nishikawa Lis Campos Ferreira Hyder Aragão de Melo Roberto César Pereira do Prado |
| author_facet | Tiago Machado Guerreiro Danilo Ryuko Cândido Nishikawa Lis Campos Ferreira Hyder Aragão de Melo Roberto César Pereira do Prado |
| author_sort | Tiago Machado Guerreiro |
| collection | DOAJ |
| description | Restless legs syndrome (RLS) is a neurological disorder that responds to dopaminergic drugs, indicating a common pathophysiology with Parkinson's disease (PD). The prevalence of RLS was estimated in a group of PD patients and its clinical and biochemical characteristics were analysed. Forty-eight patients with PD were evaluated into two groups, with and without RLS. Clinical characteristics assessed in both groups were age, gender, duration of PD, Hoehn and Yahr, and Schwab and England scales. Laboratory variables such as hemoglobin, s-iron, s-ferritin and creatinine were obtained. The prevalence of RLS was 18.75%. No significant differences regarding clinical variables and biochemical parameters were observed. The high prevalence of RLS found in PD patients suggests the concept of a common etiological link and it seems that secondary causes did not play a central role in the pathophysiology of RLS in this group of parkinsonian patients. |
| first_indexed | 2024-04-13T22:19:48Z |
| format | Article |
| id | doaj.art-0d5dd6bf245b4fb09af138332316fb02 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-13T22:19:48Z |
| publishDate | 2010-12-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-0d5dd6bf245b4fb09af138332316fb022022-12-22T02:27:16ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272010-12-0168686987210.1590/S0004-282X2010000600007S0004-282X2010000600007Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlationsTiago Machado Guerreiro0Danilo Ryuko Cândido Nishikawa1Lis Campos Ferreira2Hyder Aragão de Melo3Roberto César Pereira do Prado4Universidade Federal de SergipeUniversidade Federal de SergipeUniversidade Federal de SergipeUniversidade Federal de SergipeUniversidade Federal de SergipeRestless legs syndrome (RLS) is a neurological disorder that responds to dopaminergic drugs, indicating a common pathophysiology with Parkinson's disease (PD). The prevalence of RLS was estimated in a group of PD patients and its clinical and biochemical characteristics were analysed. Forty-eight patients with PD were evaluated into two groups, with and without RLS. Clinical characteristics assessed in both groups were age, gender, duration of PD, Hoehn and Yahr, and Schwab and England scales. Laboratory variables such as hemoglobin, s-iron, s-ferritin and creatinine were obtained. The prevalence of RLS was 18.75%. No significant differences regarding clinical variables and biochemical parameters were observed. The high prevalence of RLS found in PD patients suggests the concept of a common etiological link and it seems that secondary causes did not play a central role in the pathophysiology of RLS in this group of parkinsonian patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600007&lng=en&tlng=ensíndrome das pernas inquietasdoença de Parkinsonprevalênciaferritina |
| spellingShingle | Tiago Machado Guerreiro Danilo Ryuko Cândido Nishikawa Lis Campos Ferreira Hyder Aragão de Melo Roberto César Pereira do Prado Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations Arquivos de Neuro-Psiquiatria síndrome das pernas inquietas doença de Parkinson prevalência ferritina |
| title | Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations |
| title_full | Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations |
| title_fullStr | Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations |
| title_full_unstemmed | Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations |
| title_short | Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations |
| title_sort | restless legs syndrome in parkinson s disease clinical characteristics and biochemical correlations |
| topic | síndrome das pernas inquietas doença de Parkinson prevalência ferritina |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000600007&lng=en&tlng=en |
| work_keys_str_mv | AT tiagomachadoguerreiro restlesslegssyndromeinparkinsonsdiseaseclinicalcharacteristicsandbiochemicalcorrelations AT daniloryukocandidonishikawa restlesslegssyndromeinparkinsonsdiseaseclinicalcharacteristicsandbiochemicalcorrelations AT liscamposferreira restlesslegssyndromeinparkinsonsdiseaseclinicalcharacteristicsandbiochemicalcorrelations AT hyderaragaodemelo restlesslegssyndromeinparkinsonsdiseaseclinicalcharacteristicsandbiochemicalcorrelations AT robertocesarpereiradoprado restlesslegssyndromeinparkinsonsdiseaseclinicalcharacteristicsandbiochemicalcorrelations |