The use of psilocybin in the treatment of psychiatric disorders – review

Introduction: The word “psychedelic” derives from the Greek language and can be loosely translated as “mind manifesting” which is to convey that these substances allow the mind to unleash its hidden potential. Psilocybin is considered to be a “classic psychedelic” and is most commonly found in the...

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Main Authors: Justyna Woźniak, Rafał Bogacz, Magdalena Gaik, Ewa Uram, Inga Magda, Karol Womperski, Magdalena Osuch
Format: Article
Language:English
Published: Kazimierz Wielki University 2023-08-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/45024
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author Justyna Woźniak
Rafał Bogacz
Magdalena Gaik
Ewa Uram
Inga Magda
Karol Womperski
Magdalena Osuch
author_facet Justyna Woźniak
Rafał Bogacz
Magdalena Gaik
Ewa Uram
Inga Magda
Karol Womperski
Magdalena Osuch
author_sort Justyna Woźniak
collection DOAJ
description Introduction: The word “psychedelic” derives from the Greek language and can be loosely translated as “mind manifesting” which is to convey that these substances allow the mind to unleash its hidden potential. Psilocybin is considered to be a “classic psychedelic” and is most commonly found in the form of so-called “magic mushrooms”. Due to its unique properties psilocybin has been used during religious ceremonies and rituals for centuries and more recently also explored in a medical context. Nowadays many studies are being carried out to prove the efficacy of its use in the treatment of various psychiatric disorders.  Aim of study: Review of the current knowledge on the subject of psilocybin applied in the treatment of psychiatric disorders, such as major depressive disorder, treatment-resistant depression and addiction. Methods and materials: A review of chosen literature was carried out in the PubMed database and Google Scholar using the following phrases: psilocybin, psychedelics, psychedelic-assisted therapy, major depressive disorder, addiction. Results: Recent studies suggest that psilocybin may be an effective form of treatment for cancer-related psychiatric distress, treatment-resistant depression and addiction. There are some reports of psilocybin being useful when treating obsessive-compulsive disorder and cluster headaches. Conclusions: More large-scale, randomized, placebo-controlled studies are required to prove these promising findings. Psychological support is crucial during the treatment with psilocybin.
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spelling doaj.art-0d60482f2eaf47089b96029c3cfa5bcf2023-08-15T10:48:21ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0143110.12775/JEHS.2023.43.01.009The use of psilocybin in the treatment of psychiatric disorders – reviewJustyna Woźniak0Rafał Bogacz1Magdalena Gaik2Ewa Uram3Inga Magda4Karol Womperski5Magdalena Osuch6Wrocław Medical University, Wybrzeże L. Pasteura 1, 50-367 WrocławLower Silesian Oncology Center in Wrocław, Plac Ludwika Hirszfelda 12, 53-413 WrocławLower Silesian Oncology Center in Wrocław, Plac Ludwika Hirszfelda 12, 53-413 WrocławLower Silesian Oncology Center in Wrocław, Plac Ludwika Hirszfelda 12, 53-413 Wrocław5 Military Clinical Hospital SPZOZ, Wrocławska 1-3, 30-901 Kraków Wrocław Medical University Wybrzeże L. Pasteura 1, 50-367 WrocławJ. Dietl Specialist Hospital, Skarbowa 4, 31-121 Kraków Introduction: The word “psychedelic” derives from the Greek language and can be loosely translated as “mind manifesting” which is to convey that these substances allow the mind to unleash its hidden potential. Psilocybin is considered to be a “classic psychedelic” and is most commonly found in the form of so-called “magic mushrooms”. Due to its unique properties psilocybin has been used during religious ceremonies and rituals for centuries and more recently also explored in a medical context. Nowadays many studies are being carried out to prove the efficacy of its use in the treatment of various psychiatric disorders.  Aim of study: Review of the current knowledge on the subject of psilocybin applied in the treatment of psychiatric disorders, such as major depressive disorder, treatment-resistant depression and addiction. Methods and materials: A review of chosen literature was carried out in the PubMed database and Google Scholar using the following phrases: psilocybin, psychedelics, psychedelic-assisted therapy, major depressive disorder, addiction. Results: Recent studies suggest that psilocybin may be an effective form of treatment for cancer-related psychiatric distress, treatment-resistant depression and addiction. There are some reports of psilocybin being useful when treating obsessive-compulsive disorder and cluster headaches. Conclusions: More large-scale, randomized, placebo-controlled studies are required to prove these promising findings. Psychological support is crucial during the treatment with psilocybin. https://apcz.umk.pl/JEHS/article/view/45024psylocibinpsychodelicspsychodelic-assisted therapymajor depressive disorderaddiction
spellingShingle Justyna Woźniak
Rafał Bogacz
Magdalena Gaik
Ewa Uram
Inga Magda
Karol Womperski
Magdalena Osuch
The use of psilocybin in the treatment of psychiatric disorders – review
Journal of Education, Health and Sport
psylocibin
psychodelics
psychodelic-assisted therapy
major depressive disorder
addiction
title The use of psilocybin in the treatment of psychiatric disorders – review
title_full The use of psilocybin in the treatment of psychiatric disorders – review
title_fullStr The use of psilocybin in the treatment of psychiatric disorders – review
title_full_unstemmed The use of psilocybin in the treatment of psychiatric disorders – review
title_short The use of psilocybin in the treatment of psychiatric disorders – review
title_sort use of psilocybin in the treatment of psychiatric disorders review
topic psylocibin
psychodelics
psychodelic-assisted therapy
major depressive disorder
addiction
url https://apcz.umk.pl/JEHS/article/view/45024
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