Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review

Perivascular epithelioid cell tumors (PEComa) are a rare type of mesenchymal tumor arising from perivascular epithelial cells. These tumor cells are a co-expression of both melanocytic and myogenic antigens, such as HMB 45 and smooth muscle actin, and at least in some patients, are located around ve...

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Main Authors: Handan ÇELİK, Mehmet KEFELİ, Mehmet ÇETİNKAYA, Levent YILDIZ
Format: Article
Language:English
Published: Federation of Turkish Pathology Societies 2018-01-01
Series:Türk Patoloji Dergisi
Subjects:
Online Access:http://www.turkjpath.org/pdf.php3?id=1710
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author Handan ÇELİK
Mehmet KEFELİ
Mehmet ÇETİNKAYA
Levent YILDIZ
author_facet Handan ÇELİK
Mehmet KEFELİ
Mehmet ÇETİNKAYA
Levent YILDIZ
author_sort Handan ÇELİK
collection DOAJ
description Perivascular epithelioid cell tumors (PEComa) are a rare type of mesenchymal tumor arising from perivascular epithelial cells. These tumor cells are a co-expression of both melanocytic and myogenic antigens, such as HMB 45 and smooth muscle actin, and at least in some patients, are located around vessels. PEComas has been reported at various sites, including visceral organs, soft tissue, the prostate gland and broad ligaments. In the female reproductive system, the uterine corpus is the most common site of involvement. Some cases are related to tuberous sclerosis complex. Cervical PEComa with tuberous sclerosis complex is presented in the case of a 41 year-old and the literature is reviewed. There have been only eight cases of cervical PEComas and only one other case associated with tuberous sclerosis complex reported to date.
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spelling doaj.art-0d67e4d5f8a248319ae33244a49726042023-02-15T16:17:07ZengFederation of Turkish Pathology SocietiesTürk Patoloji Dergisi1018-56151309-57302018-01-01341828610.5146/tjpath.2014.01274Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature ReviewHandan ÇELİKMehmet KEFELİMehmet ÇETİNKAYALevent YILDIZ Perivascular epithelioid cell tumors (PEComa) are a rare type of mesenchymal tumor arising from perivascular epithelial cells. These tumor cells are a co-expression of both melanocytic and myogenic antigens, such as HMB 45 and smooth muscle actin, and at least in some patients, are located around vessels. PEComas has been reported at various sites, including visceral organs, soft tissue, the prostate gland and broad ligaments. In the female reproductive system, the uterine corpus is the most common site of involvement. Some cases are related to tuberous sclerosis complex. Cervical PEComa with tuberous sclerosis complex is presented in the case of a 41 year-old and the literature is reviewed. There have been only eight cases of cervical PEComas and only one other case associated with tuberous sclerosis complex reported to date.http://www.turkjpath.org/pdf.php3?id=1710Perivascular epithelioid cell neoplasmUterine cervical neoplasmTuberous sclerosis
spellingShingle Handan ÇELİK
Mehmet KEFELİ
Mehmet ÇETİNKAYA
Levent YILDIZ
Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review
Türk Patoloji Dergisi
Perivascular epithelioid cell neoplasm
Uterine cervical neoplasm
Tuberous sclerosis
title Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review
title_full Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review
title_fullStr Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review
title_full_unstemmed Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review
title_short Perivascular Epithelioid Cell Tumor (PEComa) of the Uterine Cervix in a Patient with Tuberous Sclerosis Complex: A Literature Review
title_sort perivascular epithelioid cell tumor pecoma of the uterine cervix in a patient with tuberous sclerosis complex a literature review
topic Perivascular epithelioid cell neoplasm
Uterine cervical neoplasm
Tuberous sclerosis
url http://www.turkjpath.org/pdf.php3?id=1710
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AT mehmetcetinkaya perivascularepithelioidcelltumorpecomaoftheuterinecervixinapatientwithtuberoussclerosiscomplexaliteraturereview
AT leventyildiz perivascularepithelioidcelltumorpecomaoftheuterinecervixinapatientwithtuberoussclerosiscomplexaliteraturereview