Escherichia coli aceE variants coding pyruvate dehydrogenase improve the generation of pyruvate‐derived acetoin

Abstract Several chromosomally expressed AceE variants were constructed in Escherichia coli ΔldhA ΔpoxB ΔppsA and compared using glucose as the sole carbon source. These variants were examined in shake flask cultures for growth rate, pyruvate accumulation, and acetoin production via heterologous exp...

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Bibliographic Details
Main Authors: W. Chris Moxley, Rachel E. Brown, Mark A. Eiteman
Format: Article
Language:English
Published: Wiley-VCH 2023-03-01
Series:Engineering in Life Sciences
Subjects:
Online Access:https://doi.org/10.1002/elsc.202200054