O-linked N-acetylglucosamine affects mitochondrial homeostasis by regulating Parkin-dependent mitophagy in hyperoxia-injured alveolar type II cells injury

Abstract Background The level of linked N-acetylglucosamine (O-GlcNAc) has been proved to be a sensor of cell state, but its relationship with hyperoxia-induced alveolar type 2 epithelial cells injure and bronchopulmonary dysplasia (BPD) has not been clarified. In this study, we evaluated if these e...

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Bibliographic Details
Main Authors: Yu Xuefei, Liu Dongyan, Li Tianming, Zheng Hejuan, Fu Jianhua
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-022-02287-0