Icariin promotes bone marrow mesenchymal stem cells osteogenic differentiation via the mTOR/autophagy pathway to improve ketogenic diet-associated osteoporosis
Abstract Background Icariin, a traditional Chinese medicine, has demonstrated anti-osteoporotic properties in ovariectomized mice. However, its effectiveness in preventing bone loss induced by ketogenic diet (KD), which mimics osteoporosis in human, remains unexplored. This study aims to investigate...
Main Authors: | Wei Liu, Shouyu Xiang, Yingcong Wu, Dinghao Zhang, Chuhai Xie, Hailan Hu, Qi Liu |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-024-04529-x |
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