Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions

Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions

Melanocytic neoplasms have been genetically characterized in detail during the last decade. Recurrent <i>CTNNB1</i> exon 3 mutations have been recognized in the distinct group of melanocytic tumors showing deep penetrating nevus-like morphology. In addition, they have been identified in...

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Bibliographic Details
Main Authors: Anne Zaremba, Philipp Jansen, Rajmohan Murali, Anand Mayakonda, Anna Riedel, Dieter Krahl, Hans Burkhardt, Stefan John, Cyrill Géraud, Manuel Philip, Julia Kretz, Inga Möller, Nadine Stadtler, Antje Sucker, Annette Paschen, Selma Ugurel, Lisa Zimmer, Elisabeth Livingstone, Susanne Horn, Christoph Plass, Dirk Schadendorf, Eva Hadaschik, Pavlo Lutsik, Klaus Griewank
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
deep penetrating nevus
deep penetrating melanoma
malignant melanoma
mutation profiling
immune checkpoint inhibition
Online Access:https://www.mdpi.com/2072-6694/14/17/4066

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