The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases

The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases

Phosphorylation by kinases governs many key cellular and extracellular processes, such as transcription, cell cycle progression, differentiation, secretion and apoptosis. Unsurprisingly, tight and precise kinase regulation is a prerequisite for normal cell functioning, whereas kinase dysregulation o...

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Bibliographic Details
Main Authors: Veronika Obsilova, Tomas Obsil
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
14-3-3
kinase
phosphorylation
RAF kinase
ASK1
CaMKK2
Online Access:https://www.mdpi.com/1422-0067/21/22/8824

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