Associations between proton pump inhibitors and Alzheimer’s disease: a nested case–control study using a Korean nationwide health screening cohort

Associations between proton pump inhibitors and Alzheimer’s disease: a nested case–control study using a Korean nationwide health screening cohort

Abstract Background Safety concerns against the use of proton pump inhibitors (PPIs) based on the risk of dementia, especially Alzheimer’s disease (AD), remain controversial. Here, we investigated the likelihood of AD depending on previous PPI exposure, use duration, and PPI generation. Methods This...

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Bibliographic Details
Main Authors: Hyo Geun Choi, Joo-Hee Kim, Ji Hee Kim, Eun Soo Kim, Ha Young Park, Kyueng-Whan Min, Mi Jung Kwon
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Dementia
Nested case–control study
Proton pump inhibitors
Online Access:https://doi.org/10.1186/s13195-022-01032-5

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