Effects of Growth Hormone Replacement on Peripheral Muscle and Exercise Capacity in Severe Growth Hormone Deficiency

Effects of Growth Hormone Replacement on Peripheral Muscle and Exercise Capacity in Severe Growth Hormone Deficiency

ObjectiveThe aim of this study is to evaluate the effect of growth hormone therapy (rGH) on mitochondrial function on peripheral muscle and to correlate with exercise capacity in subjects with severe adult growth hormone deficiency (GHD).DesignSix months, double-blind, randomized, crossover, placebo...

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Bibliographic Details
Main Authors: Susana Gonzalez, Thozhukat Sathyapalan, Zeeshan Javed, Stephen L. Atkin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Endocrinology
Subjects:
GH deficiency
succinate dehydrogenase
cardiovascular risk factors
exercise performance
mitochondrial dysfunction
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00056/full

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