Ameloblastoma of the mandible: analysis of radiographic and histopathological features
Introduction: Ameloblastoma is the most common benign tumour of odontogenic origin in Africa and presents five times more in the mandible than the maxilla. The presentation of ameloblastoma in the mandible is unique due to its anatomical variation and hence the aim of this study was to analyse the r...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2021-01-01
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| Series: | Journal of Oral Medicine and Oral Surgery |
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| Online Access: | https://www.jomos.org/articles/mbcb/full_html/2021/01/mbcb200007/mbcb200007.html |
| _version_ | 1818646914885746688 |
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| author | Ranchod Sanjay Titinchi Fadi Behardien Nashreen Morkel Jean |
| author_facet | Ranchod Sanjay Titinchi Fadi Behardien Nashreen Morkel Jean |
| author_sort | Ranchod Sanjay |
| collection | DOAJ |
| description | Introduction: Ameloblastoma is the most common benign tumour of odontogenic origin in Africa and presents five times more in the mandible than the maxilla. The presentation of ameloblastoma in the mandible is unique due to its anatomical variation and hence the aim of this study was to analyse the radiographic and histopathological features of ameloblastoma involving the mandible. Materials and methods: This was a retrospective, descriptive study of all histopathologically diagnosed ameloblastoma of the mandible over a period of 45 years. Patient demographics, radiographic and histopathological features were recorded and compared to previous studies. Results: A total of 148 lesions were included. The male to female ratio was nearly equal (1.05:1). The majority of patients were below 50 years of age (83.77%) and were black African (58.8%). The posterior region was the most affected site with majority of lesions presenting with multilocular appearance (68.24%) and root resorption (66.38%). Histologically, conventional ameloblastoma was the most common variant (48.65%). Conclusions: Mandibular ameloblastoma had a higher predilection for black African patients with higher prevalence of mixed density lesions when compared to previous studies. The size of lesions in this sample was considerably larger than those reported in previous studies. In addition, lesions in this sample also exhibited marked cortical expansion as well as root resorption. |
| first_indexed | 2024-12-17T00:54:13Z |
| format | Article |
| id | doaj.art-0d7714c726614919a3fe19edba8b7072 |
| institution | Directory Open Access Journal |
| issn | 2608-1326 |
| language | English |
| last_indexed | 2024-12-17T00:54:13Z |
| publishDate | 2021-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Journal of Oral Medicine and Oral Surgery |
| spelling | doaj.art-0d7714c726614919a3fe19edba8b70722022-12-21T22:09:38ZengEDP SciencesJournal of Oral Medicine and Oral Surgery2608-13262021-01-01271610.1051/mbcb/2020051mbcb200007Ameloblastoma of the mandible: analysis of radiographic and histopathological featuresRanchod Sanjay0Titinchi Fadi1https://orcid.org/0000-0003-3182-7038Behardien Nashreen2Morkel Jean3Department of Maxillo-Facial and Oral Surgery, Faculty of Dentistry and WHO collaborating centre, Tygerberg Oral Health Centre, University of the Western Cape, Francie van Zijl DriveDepartment of Maxillo-Facial and Oral Surgery, Faculty of Dentistry and WHO collaborating centre, Tygerberg Oral Health Centre, University of the Western Cape, Francie van Zijl DriveDepartment of Maxillo-Facial and Oral Surgery, Faculty of Dentistry and WHO collaborating centre, Tygerberg Oral Health Centre, University of the Western Cape, Francie van Zijl DriveDepartment of Maxillo-Facial and Oral Surgery, Faculty of Dentistry and WHO collaborating centre, Tygerberg Oral Health Centre, University of the Western Cape, Francie van Zijl DriveIntroduction: Ameloblastoma is the most common benign tumour of odontogenic origin in Africa and presents five times more in the mandible than the maxilla. The presentation of ameloblastoma in the mandible is unique due to its anatomical variation and hence the aim of this study was to analyse the radiographic and histopathological features of ameloblastoma involving the mandible. Materials and methods: This was a retrospective, descriptive study of all histopathologically diagnosed ameloblastoma of the mandible over a period of 45 years. Patient demographics, radiographic and histopathological features were recorded and compared to previous studies. Results: A total of 148 lesions were included. The male to female ratio was nearly equal (1.05:1). The majority of patients were below 50 years of age (83.77%) and were black African (58.8%). The posterior region was the most affected site with majority of lesions presenting with multilocular appearance (68.24%) and root resorption (66.38%). Histologically, conventional ameloblastoma was the most common variant (48.65%). Conclusions: Mandibular ameloblastoma had a higher predilection for black African patients with higher prevalence of mixed density lesions when compared to previous studies. The size of lesions in this sample was considerably larger than those reported in previous studies. In addition, lesions in this sample also exhibited marked cortical expansion as well as root resorption.https://www.jomos.org/articles/mbcb/full_html/2021/01/mbcb200007/mbcb200007.htmlameloblastomamandibleodontogenic tumour |
| spellingShingle | Ranchod Sanjay Titinchi Fadi Behardien Nashreen Morkel Jean Ameloblastoma of the mandible: analysis of radiographic and histopathological features Journal of Oral Medicine and Oral Surgery ameloblastoma mandible odontogenic tumour |
| title | Ameloblastoma of the mandible: analysis of radiographic and histopathological features |
| title_full | Ameloblastoma of the mandible: analysis of radiographic and histopathological features |
| title_fullStr | Ameloblastoma of the mandible: analysis of radiographic and histopathological features |
| title_full_unstemmed | Ameloblastoma of the mandible: analysis of radiographic and histopathological features |
| title_short | Ameloblastoma of the mandible: analysis of radiographic and histopathological features |
| title_sort | ameloblastoma of the mandible analysis of radiographic and histopathological features |
| topic | ameloblastoma mandible odontogenic tumour |
| url | https://www.jomos.org/articles/mbcb/full_html/2021/01/mbcb200007/mbcb200007.html |
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