Biological interacting units identified in human protein networks reveal tissue-functional diversification and its impact on disease

Biological interacting units identified in human protein networks reveal tissue-functional diversification and its impact on disease

Protein-protein interactions (PPI) play an essential role in the biological processes that occur in the cell. Therefore, the dissection of PPI networks becomes decisive to model functional coordination and predict pathological de-regulation. Cellular networks are dynamic and proteins display varying...

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Bibliographic Details
Main Authors: Marina L. García-Vaquero, Margarida Gama-Carvalho, Francisco R. Pinto, Javier De Las Rivas
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Biological function
Disease gene
Housekeeping gene
PPI network
Protein module
Tissue-specific gene
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002860

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