CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion
Abstract Retrospective cohort study. To validate computed tomography (CT) radiodensity in Hounsfield units (HU) as a prognostic marker for pedicle screw loosening or cage subsidence in minimally invasive transforaminal lumbar interbody fusion (MI-TLIF). The retrospective study involved 198 patients...
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Nature Portfolio
2023-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-28555-7 |
| _version_ | 1811175789418250240 |
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| author | Yu-Cheng Yao Hsien Chao Kun-Yu Kao Hsi-Hsien Lin Shih-Tien Wang Ming-Chau Chang Chien-Lin Liu Po-Hsin Chou |
| author_facet | Yu-Cheng Yao Hsien Chao Kun-Yu Kao Hsi-Hsien Lin Shih-Tien Wang Ming-Chau Chang Chien-Lin Liu Po-Hsin Chou |
| author_sort | Yu-Cheng Yao |
| collection | DOAJ |
| description | Abstract Retrospective cohort study. To validate computed tomography (CT) radiodensity in Hounsfield units (HU) as a prognostic marker for pedicle screw loosening or cage subsidence in minimally invasive transforaminal lumbar interbody fusion (MI-TLIF). The retrospective study involved 198 patients treated with MI-TLIF. Screw loosening (SL), cage subsidence (CS), and fusion status were assessed by plain radiographs. The risk factors of SL and CS were identified using logistic regression. A total of 258 levels and 930 screws were analyzed. During a 2-year follow-up, 16.2% and 24.7% of patients had CS and SL respectively. The cut-off value of L1 HU for predicting SL or CS was 117. The L1 HU < 117 and BMI ≥ 25 were two independent risk factors. The risk of SL or CS was 4.1 fold in patients L1 HU < 117 and 2.6 fold in patients with BMI ≥ 25. For patients concurrently having BMI ≥ 25 and pre-op L1 HU < 117, the risk was 4.3 fold. Fusion rate and clinical outcome were comparable in patients with SL or CS. L1 HU < 117 and BMI > 25 were two independent risk factors that can be screened preoperatively for preventing SL or CS and lead to better management of patients undergoing MI-TLIF. |
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| format | Article |
| id | doaj.art-0d79fc60d0144253a2e3c6c95f15fd90 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-10T19:42:42Z |
| publishDate | 2023-01-01 |
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| spelling | doaj.art-0d79fc60d0144253a2e3c6c95f15fd902023-01-29T12:13:12ZengNature PortfolioScientific Reports2045-23222023-01-011311910.1038/s41598-023-28555-7CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusionYu-Cheng Yao0Hsien Chao1Kun-Yu Kao2Hsi-Hsien Lin3Shih-Tien Wang4Ming-Chau Chang5Chien-Lin Liu6Po-Hsin Chou7Department of Orthopedics and Traumatology, Taipei Veterans General HospitalSchool of Medicine, National Yang Ming Chiao Tung UniversitySchool of Medicine, National Yang Ming Chiao Tung UniversityDepartment of Orthopedics and Traumatology, Taipei Veterans General HospitalDepartment of Orthopedics and Traumatology, Taipei Veterans General HospitalDepartment of Orthopedics and Traumatology, Taipei Veterans General HospitalDepartment of Orthopedics and Traumatology, Taipei Veterans General HospitalDepartment of Orthopedics and Traumatology, Taipei Veterans General HospitalAbstract Retrospective cohort study. To validate computed tomography (CT) radiodensity in Hounsfield units (HU) as a prognostic marker for pedicle screw loosening or cage subsidence in minimally invasive transforaminal lumbar interbody fusion (MI-TLIF). The retrospective study involved 198 patients treated with MI-TLIF. Screw loosening (SL), cage subsidence (CS), and fusion status were assessed by plain radiographs. The risk factors of SL and CS were identified using logistic regression. A total of 258 levels and 930 screws were analyzed. During a 2-year follow-up, 16.2% and 24.7% of patients had CS and SL respectively. The cut-off value of L1 HU for predicting SL or CS was 117. The L1 HU < 117 and BMI ≥ 25 were two independent risk factors. The risk of SL or CS was 4.1 fold in patients L1 HU < 117 and 2.6 fold in patients with BMI ≥ 25. For patients concurrently having BMI ≥ 25 and pre-op L1 HU < 117, the risk was 4.3 fold. Fusion rate and clinical outcome were comparable in patients with SL or CS. L1 HU < 117 and BMI > 25 were two independent risk factors that can be screened preoperatively for preventing SL or CS and lead to better management of patients undergoing MI-TLIF.https://doi.org/10.1038/s41598-023-28555-7 |
| spellingShingle | Yu-Cheng Yao Hsien Chao Kun-Yu Kao Hsi-Hsien Lin Shih-Tien Wang Ming-Chau Chang Chien-Lin Liu Po-Hsin Chou CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion Scientific Reports |
| title | CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion |
| title_full | CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion |
| title_fullStr | CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion |
| title_full_unstemmed | CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion |
| title_short | CT Hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion |
| title_sort | ct hounsfield unit is a reliable parameter for screws loosening or cages subsidence in minimally invasive transforaminal lumbar interbody fusion |
| url | https://doi.org/10.1038/s41598-023-28555-7 |
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