Nano-Curcumin Prevents Copper Reproductive Toxicity by Attenuating Oxidative Stress and Inflammation and Improving Nrf2/HO-1 Signaling and Pituitary-Gonadal Axis in Male Rats

Nano-Curcumin Prevents Copper Reproductive Toxicity by Attenuating Oxidative Stress and Inflammation and Improving Nrf2/HO-1 Signaling and Pituitary-Gonadal Axis in Male Rats

Copper is essential for several cellular processes and is an important catalytic factor for many proteins. However, excess copper can provoke oxidative stress and reproductive toxicity. This study evaluated the effect of liposomal nano-curcumin (N-CUR) and CUR on testicular oxidative injury, inflamm...

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Bibliographic Details
Main Authors: Wedad S. Sarawi, Ahlam M. Alhusaini, Laila M. Fadda, Hatun A. Alomar, Awatif B. Albaker, Hanan K. Alghibiwi, Amjad S. Aljrboa, Areej M. Alotaibi, Iman H. Hasan, Ayman M. Mahmoud
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Toxics
Subjects:
curcumin
reproductive toxicity
copper sulfate
steroidogenesis
oxidative stress
Online Access:https://www.mdpi.com/2305-6304/10/7/356

Internet

https://www.mdpi.com/2305-6304/10/7/356

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