Distinct roles of synaptic and extrasynaptic GABAA receptors in striatal inhibition dynamics

Distinct roles of synaptic and extrasynaptic GABAA receptors in striatal inhibition dynamics

Striatonigral and striatopallidal projecting medium spiny neurons (MSNs) express dopamine D1 (D1+) and D2 receptors (D2+), respectively. Both classes receive extensive GABAergic input via expression of synaptic, perisynaptic and extrasynaptic GABAA receptors. The activation patterns of different pre...

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Bibliographic Details
Main Authors: Ruixi eLuo, John G Partridge, Stefano eVicini
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Neural Circuits
Subjects:
GABA
Striatum
patch-clamp
tonic inhibition
Cre-lox genetics.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2013.00186/full

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