Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis
Introduction Perfusion imaging according to the DEFUSE 3 or DAWN criteria has been applied to select patients with large vascular occlusive stroke undergo endovascular therapy (EVT) in the extended time window. Emerging studies have shown that collateral blood flow-based criteria may be as effective...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-10-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/10/e059557.full |
| _version_ | 1828100110057209856 |
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| author | Yun Chen Mao Li Dongdong Yang Junyan Liu Yuling Shen Shanyu Liu |
| author_facet | Yun Chen Mao Li Dongdong Yang Junyan Liu Yuling Shen Shanyu Liu |
| author_sort | Yun Chen |
| collection | DOAJ |
| description | Introduction Perfusion imaging according to the DEFUSE 3 or DAWN criteria has been applied to select patients with large vascular occlusive stroke undergo endovascular therapy (EVT) in the extended time window. Emerging studies have shown that collateral blood flow-based criteria may be as effective as DEFUSE 3 and DAWN criteria for the evaluation of EVT eligibility beyond 6 hours. We will conduct a meta-analysis to compare collateral status-based criteria with DEFUSE 3 or DAWN criteria.Methods and analysis We will conduct a search for the studies comparing collateral blood flow-based imaging with CT perfusion using the DEFUSE 3 or DAWN criteria in selecting patients with acute ischaemic stroke undergo EVT in the Web of Science, PubMed, EMBASE and the Cochrane Library databases between November 2017 and November 2021. We will also search the sources of grey literature, the reference lists of included studies and the newly published studies during the review period. Two investigators will independently screen the eligible studies and extract data. The study quality will be assessed by using the Newcastle-Ottawa Scale or the Cochrane risk bias tool. Stata V.17 will be used to conduct data analysis.Ethics and dissemination Patient informed consent and ethics approval are not necessary as this study uses only published studies. The finding of this meta-analysis will be propagated through committee conferences or peer-reviewed journals.PROSPERO registration number CRD42021281928. |
| first_indexed | 2024-04-11T08:24:12Z |
| format | Article |
| id | doaj.art-0d88c5bc59c34c07a2e2e1ffe546e7dc |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-11T08:24:12Z |
| publishDate | 2022-10-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-0d88c5bc59c34c07a2e2e1ffe546e7dc2022-12-22T04:34:49ZengBMJ Publishing GroupBMJ Open2044-60552022-10-01121010.1136/bmjopen-2021-059557Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysisYun Chen0Mao Li1Dongdong Yang2Junyan Liu3Yuling Shen4Shanyu Liu5Department of Neurology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaDepartment of Neurology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaDepartment of Neurology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaDepartment of Neurology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaDepartment of Neurology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaDepartment of Neurology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaIntroduction Perfusion imaging according to the DEFUSE 3 or DAWN criteria has been applied to select patients with large vascular occlusive stroke undergo endovascular therapy (EVT) in the extended time window. Emerging studies have shown that collateral blood flow-based criteria may be as effective as DEFUSE 3 and DAWN criteria for the evaluation of EVT eligibility beyond 6 hours. We will conduct a meta-analysis to compare collateral status-based criteria with DEFUSE 3 or DAWN criteria.Methods and analysis We will conduct a search for the studies comparing collateral blood flow-based imaging with CT perfusion using the DEFUSE 3 or DAWN criteria in selecting patients with acute ischaemic stroke undergo EVT in the Web of Science, PubMed, EMBASE and the Cochrane Library databases between November 2017 and November 2021. We will also search the sources of grey literature, the reference lists of included studies and the newly published studies during the review period. Two investigators will independently screen the eligible studies and extract data. The study quality will be assessed by using the Newcastle-Ottawa Scale or the Cochrane risk bias tool. Stata V.17 will be used to conduct data analysis.Ethics and dissemination Patient informed consent and ethics approval are not necessary as this study uses only published studies. The finding of this meta-analysis will be propagated through committee conferences or peer-reviewed journals.PROSPERO registration number CRD42021281928.https://bmjopen.bmj.com/content/12/10/e059557.full |
| spellingShingle | Yun Chen Mao Li Dongdong Yang Junyan Liu Yuling Shen Shanyu Liu Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis BMJ Open |
| title | Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis |
| title_full | Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis |
| title_fullStr | Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis |
| title_full_unstemmed | Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis |
| title_short | Comparison between collateral status and DEFUSE 3 or DAWN criteria in patient selection for endovascular thrombectomy within 6−24 hours after stroke: a protocol for meta-analysis |
| title_sort | comparison between collateral status and defuse 3 or dawn criteria in patient selection for endovascular thrombectomy within 6 24 hours after stroke a protocol for meta analysis |
| url | https://bmjopen.bmj.com/content/12/10/e059557.full |
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