Upregulation of NOD1 and NOD2 contribute to cancer progression through the positive regulation of tumorigenicity and metastasis in human squamous cervical cancer

Upregulation of NOD1 and NOD2 contribute to cancer progression through the positive regulation of tumorigenicity and metastasis in human squamous cervical cancer

Abstract Background Metastatic cervical squamous cell carcinoma (CSCC) has poor prognosis and is recalcitrant to the current treatment strategies, which warrants the necessity to identify novel prognostic markers and therapeutic targets. Given that CSCC is a virus-induced malignancy, we hypothesized...

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Bibliographic Details
Main Authors: Yuanyuan Zhang, Ning Li, Guangwen Yuan, Hongwen Yao, Die Zhang, Nan Li, Gongyi Zhang, Yangchun Sun, Wenpeng Wang, Jia Zeng, Ningzhi Xu, Mei Liu, Lingying Wu
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Medicine
Subjects:
Cervical squamous cell carcinoma
NOD1/2
Tumorigenicity
Metastasis
IL-8
Online Access:https://doi.org/10.1186/s12916-022-02248-w

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