Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal
A total of 206 serum samples from children (3-14 years old) living in the Amador County (La Chorrera District, Province of Panama) were screened by indirect immunofluorescence antibody test (IFAT) for the presence of antibodies against Trypanosoma cruzi. Positive sera were confirmed by recombinant e...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2005-11-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000700008 |
| _version_ | 1827879927241768960 |
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| author | Azael Saldaña Franklyn Samudio Aracelis Miranda Lissette M Herrera Sara P Saavedra Lorenzo Cáceres Vicente Bayard José E Calzada |
| author_facet | Azael Saldaña Franklyn Samudio Aracelis Miranda Lissette M Herrera Sara P Saavedra Lorenzo Cáceres Vicente Bayard José E Calzada |
| author_sort | Azael Saldaña |
| collection | DOAJ |
| description | A total of 206 serum samples from children (3-14 years old) living in the Amador County (La Chorrera District, Province of Panama) were screened by indirect immunofluorescence antibody test (IFAT) for the presence of antibodies against Trypanosoma cruzi. Positive sera were confirmed by recombinant enzyme-linked immunosorbent assay (ELISA) and Western blot analysis. The presence of blood trypanosomes was investigated by hemoculture and subsequently identify by a duplex polymerase chain reaction (PCR) followed by dot blot hybridization. The results indicated a prevalence of 9.7% for trypanosome infections, a seroprevalence of 2.9% against T. cruzi and a predominance of T. rangeli infection (6.8%). The immunological and clinical implications of these findings are discussed. |
| first_indexed | 2024-03-12T18:12:55Z |
| format | Article |
| id | doaj.art-0d9bd474041846bab32d56a0c7a906e7 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:12:55Z |
| publishDate | 2005-11-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-0d9bd474041846bab32d56a0c7a906e72023-08-02T09:13:55ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602005-11-01100772973110.1590/S0074-02762005000700008Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canalAzael SaldañaFranklyn SamudioAracelis MirandaLissette M HerreraSara P SaavedraLorenzo CáceresVicente BayardJosé E CalzadaA total of 206 serum samples from children (3-14 years old) living in the Amador County (La Chorrera District, Province of Panama) were screened by indirect immunofluorescence antibody test (IFAT) for the presence of antibodies against Trypanosoma cruzi. Positive sera were confirmed by recombinant enzyme-linked immunosorbent assay (ELISA) and Western blot analysis. The presence of blood trypanosomes was investigated by hemoculture and subsequently identify by a duplex polymerase chain reaction (PCR) followed by dot blot hybridization. The results indicated a prevalence of 9.7% for trypanosome infections, a seroprevalence of 2.9% against T. cruzi and a predominance of T. rangeli infection (6.8%). The immunological and clinical implications of these findings are discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000700008Trypanosoma rangelichildren infectionPanama |
| spellingShingle | Azael Saldaña Franklyn Samudio Aracelis Miranda Lissette M Herrera Sara P Saavedra Lorenzo Cáceres Vicente Bayard José E Calzada Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal Memorias do Instituto Oswaldo Cruz Trypanosoma rangeli children infection Panama |
| title | Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal |
| title_full | Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal |
| title_fullStr | Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal |
| title_full_unstemmed | Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal |
| title_short | Predominance of Trypanosoma rangeli infection in children from a Chagas disease endemic area in the west-shore of the Panama canal |
| title_sort | predominance of trypanosoma rangeli infection in children from a chagas disease endemic area in the west shore of the panama canal |
| topic | Trypanosoma rangeli children infection Panama |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000700008 |
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