Primary Open-Angle Glaucoma and Serum Lipids
The aim of this paper was to prove the relation between serum lipid values (cholesterol, trig- lyceride, low density cholesterol, high density cholesterol and primary open -angle glaucoma. The study includes two patient groups: 50 patients with primary open-angle glaucoma and 50 patients without th...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2009-02-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/2863 |
| _version_ | 1797260801927544832 |
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| author | Suzana Pavljašević Mensura Ašćerić |
| author_facet | Suzana Pavljašević Mensura Ašćerić |
| author_sort | Suzana Pavljašević |
| collection | DOAJ |
| description |
The aim of this paper was to prove the relation between serum lipid values (cholesterol, trig- lyceride, low density cholesterol, high density cholesterol and primary open -angle glaucoma. The study includes two patient groups: 50 patients with primary open-angle glaucoma and 50 patients without this disease. However, all 100 patients were tested for serum lipid values. The research covered a period of six months (from May to December 2007.). Primary open-angle glaucoma was diagnosed with intraocular pressure values (between 20,1 and 25,6 mm Hg) measured with Schiotz tonometry. The visual field changes were confirmed with Goldmann perimetry. The gonioscopies were done for diagnosis confirmation. The serum lipid values were confirmed with enzymatic colorimetry in vitro method. U-test (Mann-Witney-Wilcox test) and t-test, as nonparametric tests, were used for statistical evaluations. The cholesterol mean value in the test group was 6,14 mol/dm1 (3,20-8,10 mol/dm3) whereas in the control group it was 5,96 mol/dm3 (2,70-8,80 mol/dm3). U-test was with negative ranks (z=-0,83 AS=0,678). The triglyceride mean value in the test group was 2,38 mol/dm3 (0,84-11,73 mol/m3) and in the control group it was 2,04 mol/dm3 (0,63-5,89 mol/dm3). U-test was with positive ranks (z=0,950 AS=0,342). High density cholesterol was average in the test group with 1,45 mol/dm3 (0,71-3,40 mol/dm3) and in the control group 1,40 mol/m3 (0,80-3,20 mol/dm3). Low density cholesterol in the test group was 3,98 mol/m3 (1,82-6,49 mol/m3) and in the control group 4,08 mol/m3 (2,69-5,69 mol/m3). These results had positive ranks according to U-test. Serum lipid values could be one of predictable factors in primary open-angle glaucoma diagnosis. Due to the patient age, cholesterol values, as common factors in primary open-angle glaucoma and atherosclerosis genesis, could be concern in the same aetiology based on dyslipidaemia as well.
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| first_indexed | 2024-04-24T23:31:06Z |
| format | Article |
| id | doaj.art-0d9ebd089a1849e287aaa5aae7f27541 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:31:06Z |
| publishDate | 2009-02-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-0d9ebd089a1849e287aaa5aae7f275412024-03-15T14:36:57ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2009-02-019110.17305/bjbms.2009.2863525Primary Open-Angle Glaucoma and Serum LipidsSuzana Pavljašević0Mensura Ašćerić1Policlinic for Eye Diseases, Public Health Institution Tuzla, Ophthalmology Department, Faculty of Medicine, University of TuzlaDepartment of Pharmacology and Toxicology, Faculty of Medicine, University of Tuzla The aim of this paper was to prove the relation between serum lipid values (cholesterol, trig- lyceride, low density cholesterol, high density cholesterol and primary open -angle glaucoma. The study includes two patient groups: 50 patients with primary open-angle glaucoma and 50 patients without this disease. However, all 100 patients were tested for serum lipid values. The research covered a period of six months (from May to December 2007.). Primary open-angle glaucoma was diagnosed with intraocular pressure values (between 20,1 and 25,6 mm Hg) measured with Schiotz tonometry. The visual field changes were confirmed with Goldmann perimetry. The gonioscopies were done for diagnosis confirmation. The serum lipid values were confirmed with enzymatic colorimetry in vitro method. U-test (Mann-Witney-Wilcox test) and t-test, as nonparametric tests, were used for statistical evaluations. The cholesterol mean value in the test group was 6,14 mol/dm1 (3,20-8,10 mol/dm3) whereas in the control group it was 5,96 mol/dm3 (2,70-8,80 mol/dm3). U-test was with negative ranks (z=-0,83 AS=0,678). The triglyceride mean value in the test group was 2,38 mol/dm3 (0,84-11,73 mol/m3) and in the control group it was 2,04 mol/dm3 (0,63-5,89 mol/dm3). U-test was with positive ranks (z=0,950 AS=0,342). High density cholesterol was average in the test group with 1,45 mol/dm3 (0,71-3,40 mol/dm3) and in the control group 1,40 mol/m3 (0,80-3,20 mol/dm3). Low density cholesterol in the test group was 3,98 mol/m3 (1,82-6,49 mol/m3) and in the control group 4,08 mol/m3 (2,69-5,69 mol/m3). These results had positive ranks according to U-test. Serum lipid values could be one of predictable factors in primary open-angle glaucoma diagnosis. Due to the patient age, cholesterol values, as common factors in primary open-angle glaucoma and atherosclerosis genesis, could be concern in the same aetiology based on dyslipidaemia as well. https://www.bjbms.org/ojs/index.php/bjbms/article/view/2863serum lipidsprimary open-angle glaucomacholesteroltriglyceride |
| spellingShingle | Suzana Pavljašević Mensura Ašćerić Primary Open-Angle Glaucoma and Serum Lipids Biomolecules & Biomedicine serum lipids primary open-angle glaucoma cholesterol triglyceride |
| title | Primary Open-Angle Glaucoma and Serum Lipids |
| title_full | Primary Open-Angle Glaucoma and Serum Lipids |
| title_fullStr | Primary Open-Angle Glaucoma and Serum Lipids |
| title_full_unstemmed | Primary Open-Angle Glaucoma and Serum Lipids |
| title_short | Primary Open-Angle Glaucoma and Serum Lipids |
| title_sort | primary open angle glaucoma and serum lipids |
| topic | serum lipids primary open-angle glaucoma cholesterol triglyceride |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/2863 |
| work_keys_str_mv | AT suzanapavljasevic primaryopenangleglaucomaandserumlipids AT mensuraasceric primaryopenangleglaucomaandserumlipids |