Potential of medicinal plants to treat dengue
Dengue is a major public health challenge worldwide, particularly in tropical areas. Nearly 390 million infections and 22,000 deaths occur every year. At present, there are no specific therapeutics available to treat dengue; however, possible treatment procedures are explained in the traditional med...
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| Format: | Article |
| Language: | English |
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Veterinary World
2019-10-01
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| Series: | International Journal of One Health |
| Subjects: | |
| Online Access: | http://www.onehealthjournal.org/Vol.5/13.pdf |
| _version_ | 1819076837874073600 |
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| author | Dulanjalee Neelawala Sanjaya Rajapakse Wikum Widuranga Kumbukgolla |
| author_facet | Dulanjalee Neelawala Sanjaya Rajapakse Wikum Widuranga Kumbukgolla |
| author_sort | Dulanjalee Neelawala |
| collection | DOAJ |
| description | Dengue is a major public health challenge worldwide, particularly in tropical areas. Nearly 390 million infections and 22,000 deaths occur every year. At present, there are no specific therapeutics available to treat dengue; however, possible treatment procedures are explained in the traditional medical systems (TMSs), such as Sri Lankan TMS, Indian Ayurvedic, Unani, and Siddha TMS. In these TMSs, medicinal plants have been used in several ways against dengue, such as virocides, larvicides, and mosquito repellents. Therefore, medicinal plants inherit biologically active compounds/lead compounds that are yet to be identified chemically and physiologically. Herein, we discuss the possible applications of crude plant extracts and isolated phytochemicals from medicinal plants such as quercetin, sulfated galactomannans, flavonoids, and glabranine in controlling dengue. Moreover, medicinal plant-based therapeutics can be safer, cost-effective, and non-toxic. Therefore, this paper reviews the medicinal plants that are used in TMSs to manage dengue, the phytochemicals they contain, and mode of action of these phytochemicals such as virocides, larvicides, and mosquito repellents. |
| first_indexed | 2024-12-21T18:47:39Z |
| format | Article |
| id | doaj.art-0d9ee139e73745d9956aae4c8218e7f3 |
| institution | Directory Open Access Journal |
| issn | 2455-5673 2455-8931 |
| language | English |
| last_indexed | 2024-12-21T18:47:39Z |
| publishDate | 2019-10-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | International Journal of One Health |
| spelling | doaj.art-0d9ee139e73745d9956aae4c8218e7f32022-12-21T18:53:50ZengVeterinary WorldInternational Journal of One Health2455-56732455-89312019-10-015869110.14202/IJOH.2019.86-91Potential of medicinal plants to treat dengueDulanjalee Neelawala0Sanjaya Rajapakse1Wikum Widuranga Kumbukgolla2Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura 50000, Sri Lanka.Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura 50000, Sri Lanka.Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura 50000, Sri Lanka.Dengue is a major public health challenge worldwide, particularly in tropical areas. Nearly 390 million infections and 22,000 deaths occur every year. At present, there are no specific therapeutics available to treat dengue; however, possible treatment procedures are explained in the traditional medical systems (TMSs), such as Sri Lankan TMS, Indian Ayurvedic, Unani, and Siddha TMS. In these TMSs, medicinal plants have been used in several ways against dengue, such as virocides, larvicides, and mosquito repellents. Therefore, medicinal plants inherit biologically active compounds/lead compounds that are yet to be identified chemically and physiologically. Herein, we discuss the possible applications of crude plant extracts and isolated phytochemicals from medicinal plants such as quercetin, sulfated galactomannans, flavonoids, and glabranine in controlling dengue. Moreover, medicinal plant-based therapeutics can be safer, cost-effective, and non-toxic. Therefore, this paper reviews the medicinal plants that are used in TMSs to manage dengue, the phytochemicals they contain, and mode of action of these phytochemicals such as virocides, larvicides, and mosquito repellents.http://www.onehealthjournal.org/Vol.5/13.pdfdenguein silicolarvicidesphytochemicalsvirocides |
| spellingShingle | Dulanjalee Neelawala Sanjaya Rajapakse Wikum Widuranga Kumbukgolla Potential of medicinal plants to treat dengue International Journal of One Health dengue in silico larvicides phytochemicals virocides |
| title | Potential of medicinal plants to treat dengue |
| title_full | Potential of medicinal plants to treat dengue |
| title_fullStr | Potential of medicinal plants to treat dengue |
| title_full_unstemmed | Potential of medicinal plants to treat dengue |
| title_short | Potential of medicinal plants to treat dengue |
| title_sort | potential of medicinal plants to treat dengue |
| topic | dengue in silico larvicides phytochemicals virocides |
| url | http://www.onehealthjournal.org/Vol.5/13.pdf |
| work_keys_str_mv | AT dulanjaleeneelawala potentialofmedicinalplantstotreatdengue AT sanjayarajapakse potentialofmedicinalplantstotreatdengue AT wikumwidurangakumbukgolla potentialofmedicinalplantstotreatdengue |