Sarcomatoid carcinoma of the gallbladder: a case report

Sarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence r...

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Main Authors: Yunfu Shi, Jiabin Chen, Hua Chen, Xiufang Hong
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520935283
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author Yunfu Shi
Jiabin Chen
Hua Chen
Xiufang Hong
author_facet Yunfu Shi
Jiabin Chen
Hua Chen
Xiufang Hong
author_sort Yunfu Shi
collection DOAJ
description Sarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence rate, and a worse prognosis than adenocarcinoma. This report describes a 60-year-old woman with poorly differentiated adenocarcinoma of the gallbladder. She underwent treatment with chemotherapy and surgery. Palliative surgery was performed for treatment of tumor recurrence in April 2018. Postoperative pathology showed infiltration of poorly differentiated carcinomas, most of which were sarcomatoid. After four cycles of chemotherapy, the disease continued to progress. Anlotinib tablets were given from August 2018 to November 2018 but were then stopped because of gastrointestinal bleeding. The patient died in April 2019. This paper reports the whole process of diagnosis and treatment in this case of gallbladder sarcomatoid carcinoma, thus providing a reference for treatment.
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spelling doaj.art-0d9f0e2e4e8f44d0b9d17f2f20a5b6742022-12-21T19:50:54ZengSAGE PublishingJournal of International Medical Research1473-23002020-06-014810.1177/0300060520935283Sarcomatoid carcinoma of the gallbladder: a case reportYunfu ShiJiabin ChenHua ChenXiufang HongSarcomatoid carcinoma is a rare type of gallbladder cancer with no specific clinical manifestation. The final diagnosis depends on pathological and immunohistochemical examination. Sarcomatoid carcinoma is characterized by early lymphatic metastasis, rapid progression, a high short-term recurrence rate, and a worse prognosis than adenocarcinoma. This report describes a 60-year-old woman with poorly differentiated adenocarcinoma of the gallbladder. She underwent treatment with chemotherapy and surgery. Palliative surgery was performed for treatment of tumor recurrence in April 2018. Postoperative pathology showed infiltration of poorly differentiated carcinomas, most of which were sarcomatoid. After four cycles of chemotherapy, the disease continued to progress. Anlotinib tablets were given from August 2018 to November 2018 but were then stopped because of gastrointestinal bleeding. The patient died in April 2019. This paper reports the whole process of diagnosis and treatment in this case of gallbladder sarcomatoid carcinoma, thus providing a reference for treatment.https://doi.org/10.1177/0300060520935283
spellingShingle Yunfu Shi
Jiabin Chen
Hua Chen
Xiufang Hong
Sarcomatoid carcinoma of the gallbladder: a case report
Journal of International Medical Research
title Sarcomatoid carcinoma of the gallbladder: a case report
title_full Sarcomatoid carcinoma of the gallbladder: a case report
title_fullStr Sarcomatoid carcinoma of the gallbladder: a case report
title_full_unstemmed Sarcomatoid carcinoma of the gallbladder: a case report
title_short Sarcomatoid carcinoma of the gallbladder: a case report
title_sort sarcomatoid carcinoma of the gallbladder a case report
url https://doi.org/10.1177/0300060520935283
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AT jiabinchen sarcomatoidcarcinomaofthegallbladderacasereport
AT huachen sarcomatoidcarcinomaofthegallbladderacasereport
AT xiufanghong sarcomatoidcarcinomaofthegallbladderacasereport