Beneficial Impacts of Incorporating the Non-Natural Amino Acid Azulenyl-Alanine into the Trp-Rich Antimicrobial Peptide buCATHL4B
Antimicrobial peptides (AMPs) present a promising scaffold for the development of potent antimicrobial agents. Substitution of tryptophan by non-natural amino acid Azulenyl-Alanine (AzAla) would allow studying the mechanism of action of AMPs by using unique properties of this amino acid, such as abi...
Main Authors: | Areetha R. D’Souza, Matthew R. Necelis, Alona Kulesha, Gregory A. Caputo, Olga V. Makhlynets |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/3/421 |
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