An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice
Objectives: Separate exposure to microwaves (MWs) or heat had effects on expression levels of Bax and Bcl-2 and sperm parameters in studied group. Aims: The objectives of this research were to determine the effects of separate and combined exposure to 900-MHz MW (as representative of cell phone radi...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
|
| Series: | Journal of Human Reproductive Sciences |
| Subjects: | |
| Online Access: | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2017;volume=10;issue=2;spage=128;epage=134;aulast=Gohari |
| _version_ | 1819125578920361984 |
|---|---|
| author | Faezeh A Gohari Behzad Saranjam Mohsen Asgari Leila Omidi Hamid Ekrami Seyyed Ali Moussavi-Najarkola |
| author_facet | Faezeh A Gohari Behzad Saranjam Mohsen Asgari Leila Omidi Hamid Ekrami Seyyed Ali Moussavi-Najarkola |
| author_sort | Faezeh A Gohari |
| collection | DOAJ |
| description | Objectives: Separate exposure to microwaves (MWs) or heat had effects on expression levels of Bax and Bcl-2 and sperm parameters in studied group. Aims: The objectives of this research were to determine the effects of separate and combined exposure to 900-MHz MW (as representative of cell phone radiation) and heat on gene expression and spermogram of male mice. Settings and Design: This experimental animal study was conducted in the school of public health. Materials and Methods: The study was done on 12 male mice randomly divided into four groups (21–23 g): control, test group 1 with separate exposure to 900-MHz MW, test group 2 with separate exposure to hot and sultry climate, and test group 3 with simultaneous whole body exposures to 900-MHz MW and hot and sultry climate. In all studied groups, gene expression and sperm parameters were measured. Results: Tissue samples in all test groups showed integrity of the seminiferous tubule followed by all types of germ line cells. Significant increases in the number of dead sperms in mice with separate exposure to heat were observed in comparison with the other studied groups (P < 0.05). The ratio of Bax expression was elevated to 0.015 ± 0.006 in mice after combined exposures to 900-MHz MW and heat. Conclusion: Separate and combined exposure to 900-MHz MW and heat may induce adverse effects on sperm parameters and gene expression of studied male mice. |
| first_indexed | 2024-12-22T07:42:22Z |
| format | Article |
| id | doaj.art-0da5d92ff41245509e508f82b4bb94d2 |
| institution | Directory Open Access Journal |
| issn | 0974-1208 1998-4766 |
| language | English |
| last_indexed | 2024-12-22T07:42:22Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Human Reproductive Sciences |
| spelling | doaj.art-0da5d92ff41245509e508f82b4bb94d22022-12-21T18:33:43ZengWolters Kluwer Medknow PublicationsJournal of Human Reproductive Sciences0974-12081998-47662017-01-0110212813410.4103/jhrs.JHRS_136_16An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in miceFaezeh A GohariBehzad SaranjamMohsen AsgariLeila OmidiHamid EkramiSeyyed Ali Moussavi-NajarkolaObjectives: Separate exposure to microwaves (MWs) or heat had effects on expression levels of Bax and Bcl-2 and sperm parameters in studied group. Aims: The objectives of this research were to determine the effects of separate and combined exposure to 900-MHz MW (as representative of cell phone radiation) and heat on gene expression and spermogram of male mice. Settings and Design: This experimental animal study was conducted in the school of public health. Materials and Methods: The study was done on 12 male mice randomly divided into four groups (21–23 g): control, test group 1 with separate exposure to 900-MHz MW, test group 2 with separate exposure to hot and sultry climate, and test group 3 with simultaneous whole body exposures to 900-MHz MW and hot and sultry climate. In all studied groups, gene expression and sperm parameters were measured. Results: Tissue samples in all test groups showed integrity of the seminiferous tubule followed by all types of germ line cells. Significant increases in the number of dead sperms in mice with separate exposure to heat were observed in comparison with the other studied groups (P < 0.05). The ratio of Bax expression was elevated to 0.015 ± 0.006 in mice after combined exposures to 900-MHz MW and heat. Conclusion: Separate and combined exposure to 900-MHz MW and heat may induce adverse effects on sperm parameters and gene expression of studied male mice.http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2017;volume=10;issue=2;spage=128;epage=134;aulast=GohariCombined exposuregene expressionheatmicrowavesperm parameters |
| spellingShingle | Faezeh A Gohari Behzad Saranjam Mohsen Asgari Leila Omidi Hamid Ekrami Seyyed Ali Moussavi-Najarkola An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice Journal of Human Reproductive Sciences Combined exposure gene expression heat microwave sperm parameters |
| title | An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice |
| title_full | An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice |
| title_fullStr | An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice |
| title_full_unstemmed | An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice |
| title_short | An experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice |
| title_sort | experimental study of the effects of combined exposure to microwave and heat on gene expression and sperm parameters in mice |
| topic | Combined exposure gene expression heat microwave sperm parameters |
| url | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2017;volume=10;issue=2;spage=128;epage=134;aulast=Gohari |
| work_keys_str_mv | AT faezehagohari anexperimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT behzadsaranjam anexperimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT mohsenasgari anexperimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT leilaomidi anexperimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT hamidekrami anexperimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT seyyedalimoussavinajarkola anexperimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT faezehagohari experimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT behzadsaranjam experimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT mohsenasgari experimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT leilaomidi experimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT hamidekrami experimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice AT seyyedalimoussavinajarkola experimentalstudyoftheeffectsofcombinedexposuretomicrowaveandheatongeneexpressionandspermparametersinmice |