Chloride Intracellular Channel Proteins (CLICs) and Malignant Tumor Progression: A Focus on the Preventive Role of CLIC2 in Invasion and Metastasis

Chloride Intracellular Channel Proteins (CLICs) and Malignant Tumor Progression: A Focus on the Preventive Role of CLIC2 in Invasion and Metastasis

CLICs are the dimorphic protein present in both soluble and membrane fractions. As an integral membrane protein, CLICs potentially possess ion channel activity. However, it is not fully clarified what kinds of roles CLICs play in physiological and pathological conditions. In vertebrates, CLICs are c...

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Bibliographic Details
Main Authors: Saya Ozaki, Kanta Mikami, Takeharu Kunieda, Junya Tanaka
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
metastasis
invasion
MMP
MT1-MMP
CLIC4
glioma
Online Access:https://www.mdpi.com/2072-6694/14/19/4890

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