RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW

Background: Globally, 9,052 new cases of leprosy in children were reported, with a corresponding rate of 4.5 per million child population. Children are believed to be the most vulnerable group to M. leprae infections due to their immature immunity. Purpose: This study aims to determine the relations...

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Main Authors: Aisyah Noer Auliyah Madani Pertiwi, Santi Martini, Nayla Mohamed Gomaa Nasr
Format: Article
Language:English
Published: Universitas Airlangga 2024-01-01
Series:Jurnal Berkala Epidemiologi
Subjects:
Online Access:https://doi.org/10.20473/jbe.V12I12024.1-8
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author Aisyah Noer Auliyah Madani Pertiwi
Santi Martini
Nayla Mohamed Gomaa Nasr
author_facet Aisyah Noer Auliyah Madani Pertiwi
Santi Martini
Nayla Mohamed Gomaa Nasr
author_sort Aisyah Noer Auliyah Madani Pertiwi
collection DOAJ
description Background: Globally, 9,052 new cases of leprosy in children were reported, with a corresponding rate of 4.5 per million child population. Children are believed to be the most vulnerable group to M. leprae infections due to their immature immunity. Purpose: This study aims to determine the relationship between the history of BCG vaccination and leprosy incidence in children. Methods: This study used a literature review method that involved a systematic search. The data sources were obtained using several databases, namely Google Scholar, Proquest, Science Direct, and Pubmed. Keywords were built using the PICOS protocol and Boolean Operators, so the keywords used were "relationship" AND "BCG vaccine" AND "leprosy" AND "children". The research selection and search procedures were explained using the PRISMA 2020 method and research included in this study following the inclusion and exclusion criteria that have been set. Results: There were eight studies suitable for inclusion in this literature review. Five articles concluded that there was a relationship between the history of BCG vaccine and the incidence of leprosy in children, while three articles concluded that there was no relationship between the two variables. Conclusion: The BCG vaccine is useful as an effort to prevent the transmission and spread of leprosy in children. Children who do not receive BCG immunization are more susceptible to leprosy than those who receive immunization. The BCG vaccine has a protective effect to prevent children from contracting and transmitting leprosy to other people.
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spelling doaj.art-0daba20a696942c48a1a9578ba2c8fe52024-02-11T12:59:02ZengUniversitas AirlanggaJurnal Berkala Epidemiologi2301-71712541-092X2024-01-011211810.20473/jbe.V12I12024.1-8RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEWAisyah Noer Auliyah Madani Pertiwi0https://orcid.org/0009-0008-2529-7521Santi Martini1https://orcid.org/0000-0003-2424-1776Nayla Mohamed Gomaa Nasr2https://orcid.org/0000-0001-9512-3094Faculty of Public Health, Universitas AirlanggaFaculty of Public Health, Universitas AirlanggaUniversitas Debrecen, HungaryBackground: Globally, 9,052 new cases of leprosy in children were reported, with a corresponding rate of 4.5 per million child population. Children are believed to be the most vulnerable group to M. leprae infections due to their immature immunity. Purpose: This study aims to determine the relationship between the history of BCG vaccination and leprosy incidence in children. Methods: This study used a literature review method that involved a systematic search. The data sources were obtained using several databases, namely Google Scholar, Proquest, Science Direct, and Pubmed. Keywords were built using the PICOS protocol and Boolean Operators, so the keywords used were "relationship" AND "BCG vaccine" AND "leprosy" AND "children". The research selection and search procedures were explained using the PRISMA 2020 method and research included in this study following the inclusion and exclusion criteria that have been set. Results: There were eight studies suitable for inclusion in this literature review. Five articles concluded that there was a relationship between the history of BCG vaccine and the incidence of leprosy in children, while three articles concluded that there was no relationship between the two variables. Conclusion: The BCG vaccine is useful as an effort to prevent the transmission and spread of leprosy in children. Children who do not receive BCG immunization are more susceptible to leprosy than those who receive immunization. The BCG vaccine has a protective effect to prevent children from contracting and transmitting leprosy to other people.https://doi.org/10.20473/jbe.V12I12024.1-8leprosychildrenbgc vaccineprismaimmunization
spellingShingle Aisyah Noer Auliyah Madani Pertiwi
Santi Martini
Nayla Mohamed Gomaa Nasr
RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW
Jurnal Berkala Epidemiologi
leprosy
children
bgc vaccine
prisma
immunization
title RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW
title_full RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW
title_fullStr RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW
title_full_unstemmed RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW
title_short RELATIONSHIP BETWEEN BCG VACCINATION HISTORY AND THE INCIDENCE OF LEPROSY IN CHILDREN: A LITERATURE REVIEW
title_sort relationship between bcg vaccination history and the incidence of leprosy in children a literature review
topic leprosy
children
bgc vaccine
prisma
immunization
url https://doi.org/10.20473/jbe.V12I12024.1-8
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