Chronic Myelogenous Leukemia with Double Philadelphia Chromosome and Coexpression of p210 and p190 Fusion Transcripts

Chronic Myelogenous Leukemia with Double Philadelphia Chromosome and Coexpression of p210 and p190 Fusion Transcripts

The Philadelphia (Ph+) chromosome, t(9;22)(q34;q11.2), originates from a chimeric gene called <i>BCR-ABL</i> and is present in more than 90% of CML patients. Most patients with CML express the protein p210 <i>BCR-ABL</i> and, with a frequency lower than 5%, express rare isofo...

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Bibliographic Details
Main Authors: Samara Silveira da Cruz, Aline Damasceno Seabra, Lais Helena Rescinho Macambira, Débora Monteiro Carneiro, Patrícia Ferreira Nunes, Thais Brilhante Pontes, Fernando Augusto Rodrigues Mello-Junior, Lucyana Barbosa Cardoso Leão, Fernanda de Nazaré Cardoso dos Santos Cordeiro, Thiago Xavier Carneiro, Caroline Aquino Moreira-Nunes, Rommel Mario Rodríguez Burbano
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Genes
Subjects:
chronic myeloid leukemia
blast crisis
double Philadelphia chromosome
p210 and p190 coexpression
Online Access:https://www.mdpi.com/2073-4425/13/4/580

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