Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis

Exploring NK cell receptor dynamics in paediatric leukaemias: implications for immunotherapy and prognosis

Abstract Objectives Immunotherapies targeting natural killer (NK) cell receptors have shown promise against leukaemia. Unfortunately, cancer immunosuppressive mechanisms that alter NK cell phenotype prevent such approaches from being successful. The study utilises advanced cytometry to examine how c...

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Bibliographic Details
Main Authors: Cui Tu, Irina Buckle, Ingrid Leal Rojas, Gustavo Rodrigues Rossi, David P Sester, Andrew S Moore, Kristen Radford, Camille Guillerey, Fernando Souza‐Fonseca‐Guimaraes
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Clinical & Translational Immunology
Subjects:
AML
B‐ALL
NK cells
NKG2A
Online Access:https://doi.org/10.1002/cti2.1501

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